| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | TNNI3 | Thr143 | RGKFKRPtLRRVRIS | phosphorylation down-regulates | 18550549 | SIGNOR-178888 |
| PRKCD | TNNI3 | Thr143 | RGKFKRPtLRRVRIS | phosphorylation down-regulates | 24585778 | SIGNOR-204666 |
| STK4 | TNNI3 | Thr143 | RGKFKRPtLRRVRIS | phosphorylation unknown | 18986304 | SIGNOR-182053 |
| PRKCB | TNNI3 | Thr143 | RGKFKRPtLRRVRIS | phosphorylation down-regulates | 17010989 | SIGNOR-149957 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | phosphorylation up-regulates → | TNNI3 PThr143 | phosphorylation down-regulates ⊣ | TNNI3 | 18550549 | SIGNOR-178888 |
| PRKCD | phosphorylation up-regulates → | TNNI3 PThr143 | phosphorylation down-regulates ⊣ | TNNI3 | 24585778 | SIGNOR-204666 |
| STK4 | phosphorylation up-regulates → | TNNI3 PThr143 | phosphorylation down-regulates ⊣ | TNNI3 | 18986304 | SIGNOR-182053 |
| PRKCB | phosphorylation up-regulates → | TNNI3 PThr143 | phosphorylation down-regulates ⊣ | TNNI3 | 17010989 | SIGNOR-149957 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCD | phosphorylation down-regulates | TNNI3 | SIGNOR-178888 |
| PRKCD | phosphorylation down-regulates | TNNI3 | SIGNOR-204666 |
| STK4 | phosphorylation → unknown | TNNI3 | SIGNOR-182053 |
| PRKCB | phosphorylation down-regulates | TNNI3 | SIGNOR-149957 |
