| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | TNNI3 | Ser44 | KKSKISAsRKLQLKT | phosphorylation down-regulates | 15769444 | SIGNOR-134628 |
| PRKCA | TNNI3 | Ser44 | KKSKISAsRKLQLKT | phosphorylation down-regulates | 15769444 | SIGNOR-134617 |
| PRKCG | TNNI3 | Ser44 | KKSKISAsRKLQLKT | phosphorylation down-regulates | 15769444 | SIGNOR-134636 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | TNNI3 PSer44 | phosphorylation down-regulates ⊣ | TNNI3 | 15769444 | SIGNOR-134628 |
| PRKCA | phosphorylation up-regulates → | TNNI3 PSer44 | phosphorylation down-regulates ⊣ | TNNI3 | 15769444 | SIGNOR-134617 |
| PRKCG | phosphorylation up-regulates → | TNNI3 PSer44 | phosphorylation down-regulates ⊣ | TNNI3 | 15769444 | SIGNOR-134636 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation down-regulates | TNNI3 | SIGNOR-134628 |
| PRKCA | phosphorylation down-regulates | TNNI3 | SIGNOR-134617 |
| PRKCG | phosphorylation down-regulates | TNNI3 | SIGNOR-134636 |
