| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EIF2AK2 | EIF2AK2 | Tyr293 | HRIDGKTyVIKRVKY | phosphorylation up-regulates activity | 16373505 | SIGNOR-251114 |
| EIF2AK2 | EIF2AK2 | Tyr293 | HRIDGKTyVIKRVKY | phosphorylation up-regulates activity | 16373505 | SIGNOR-260784 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EIF2AK2 | phosphorylation up-regulates → | EIF2AK2 PTyr293 | phosphorylation up-regulates → | EIF2AK2 | 16373505 | SIGNOR-251114 |
| EIF2AK2 | phosphorylation up-regulates → | EIF2AK2 PTyr293 | phosphorylation up-regulates → | EIF2AK2 | 16373505 | SIGNOR-260784 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EIF2AK2 | phosphorylation → up-regulates activity | EIF2AK2 | SIGNOR-251114 |
| EIF2AK2 | phosphorylation → up-regulates activity | EIF2AK2 | SIGNOR-260784 |
