| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA3 | SLC9A1 | Ser703 | MSRARIGsDPLAYEP | phosphorylation up-regulates activity | 30377223 | SIGNOR-280119 |
| SGK1 | SLC9A1 | Ser703 | MSRARIGsDPLAYEP | phosphorylation up-regulates activity | 25270604 | SIGNOR-280123 |
| MAPK14 | SLC9A1 | Ser729 | ASPQSPEsVDLVNEE | phosphorylation up-regulates | 18701649 | SIGNOR-180048 |
| MAPK14 | SLC9A1 | Ser726 | IDPASPQsPESVDLV | phosphorylation up-regulates | 18701649 | SIGNOR-180044 |
| ROCK1 | SLC9A1 | – | phosphorylation up-regulates activity | 27302366 | SIGNOR-279566 | |
| MAPK14 | SLC9A1 | Ser726 | IDPASPQsPESVDLV | phosphorylation up-regulates | 11604491 | SIGNOR-111043 |
| MAPK14 | SLC9A1 | Thr718 | KEDLPVItIDPASPQ | phosphorylation up-regulates | 11604491 | SIGNOR-111051 |
| MAPK1 | SLC9A1 | Ser770 | MMRSKETsSPGTDDV | phosphorylation up-regulates | 17209041 | SIGNOR-151925 |
| RPS6KA1 | SLC9A1 | Ser703 | MSRARIGsDPLAYEP | phosphorylation up-regulates | 10400637 | SIGNOR-69171 |
| MAP3K14 | SLC9A1 | – | phosphorylation up-regulates activity | 11369779 | SIGNOR-279632 | |
| RPS6K | SLC9A1 | Ser703 | MSRARIGsDPLAYEP | phosphorylation up-regulates | 10400637 | SIGNOR-252792 |
| MAPK14 | SLC9A1 | Ser723 | VITIDPAsPQSPESV | phosphorylation up-regulates | 11604491 | SIGNOR-111039 |
| MAPK14 | SLC9A1 | Ser729 | ASPQSPEsVDLVNEE | phosphorylation up-regulates | 11604491 | SIGNOR-111047 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA3 | phosphorylation up-regulates → | SLC9A1 PSer703 | phosphorylation up-regulates → | SLC9A1 | 30377223 | SIGNOR-280119 |
| SGK1 | phosphorylation up-regulates → | SLC9A1 PSer703 | phosphorylation up-regulates → | SLC9A1 | 25270604 | SIGNOR-280123 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer729 | phosphorylation up-regulates → | SLC9A1 | 18701649 | SIGNOR-180048 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer726 | phosphorylation up-regulates → | SLC9A1 | 18701649 | SIGNOR-180044 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer726 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111043 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PThr718 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111051 |
| MAPK1 | phosphorylation up-regulates → | SLC9A1 PSer770 | phosphorylation up-regulates → | SLC9A1 | 17209041 | SIGNOR-151925 |
| RPS6KA1 | phosphorylation up-regulates → | SLC9A1 PSer703 | phosphorylation up-regulates → | SLC9A1 | 10400637 | SIGNOR-69171 |
| RPS6K | phosphorylation up-regulates → | SLC9A1 PSer703 | phosphorylation up-regulates → | SLC9A1 | 10400637 | SIGNOR-252792 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer723 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111039 |
| MAPK14 | phosphorylation up-regulates → | SLC9A1 PSer729 | phosphorylation up-regulates → | SLC9A1 | 11604491 | SIGNOR-111047 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA3 | phosphorylation → up-regulates activity | SLC9A1 | SIGNOR-280119 |
| SGK1 | phosphorylation → up-regulates activity | SLC9A1 | SIGNOR-280123 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-180048 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-180044 |
| ROCK1 | phosphorylation → up-regulates activity | SLC9A1 | SIGNOR-279566 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111043 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111051 |
| MAPK1 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-151925 |
| RPS6KA1 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-69171 |
| MAP3K14 | phosphorylation → up-regulates activity | SLC9A1 | SIGNOR-279632 |
| RPS6K | phosphorylation → up-regulates | SLC9A1 | SIGNOR-252792 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111039 |
| MAPK14 | phosphorylation → up-regulates | SLC9A1 | SIGNOR-111047 |
