| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | BCL3 | Ser122 | CPMEHPLsADIAMAT | phosphorylation up-regulates activity | 28689659 | SIGNOR-277360 |
| MAPK1 | BCL3 | Ser454 | PSPAPGGs | phosphorylation up-regulates activity | 28689659 | SIGNOR-277361 |
| GSK3A | BCL3 | Ser406 | PSSSPSQsPPRDPPG | phosphorylation down-regulates quantity by destabilization | 15469820 | SIGNOR-276012 |
| CHUK | BCL3 | Ser122 | CPMEHPLsADIAMAT | phosphorylation up-regulates activity | 28689659 | SIGNOR-277362 |
| AKT2 | BCL3 | Ser41 | KRPLRAPsPEPAAPR | phosphorylation up-regulates quantity by stabilization | 28689659 | SIGNOR-277359 |
| AKT1 | BCL3 | Ser41 | KRPLRAPsPEPAAPR | phosphorylation up-regulates quantity by stabilization | 28689659 | SIGNOR-277358 |
| IKBKB | BCL3 | Ser122 | CPMEHPLsADIAMAT | phosphorylation up-regulates activity | 28689659 | SIGNOR-277364 |
| GSK3A | BCL3 | Ser402 | LSASPSSsPSQSPPR | phosphorylation down-regulates quantity by destabilization | 15469820 | SIGNOR-276011 |
| CHUK | BCL3 | Ser454 | PSPAPGGs | phosphorylation up-regulates activity | 28689659 | SIGNOR-277363 |
| IKBKB | BCL3 | Ser454 | PSPAPGGs | phosphorylation up-regulates activity | 28689659 | SIGNOR-277365 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | BCL3 PSer122 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277360 |
| MAPK1 | phosphorylation up-regulates → | BCL3 PSer454 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277361 |
| GSK3A | phosphorylation up-regulates → | BCL3 PSer406 | phosphorylation down-regulates ⊣ | BCL3 | 15469820 | SIGNOR-276012 |
| CHUK | phosphorylation up-regulates → | BCL3 PSer122 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277362 |
| AKT2 | phosphorylation up-regulates → | BCL3 PSer41 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277359 |
| AKT1 | phosphorylation up-regulates → | BCL3 PSer41 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277358 |
| IKBKB | phosphorylation up-regulates → | BCL3 PSer122 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277364 |
| GSK3A | phosphorylation up-regulates → | BCL3 PSer402 | phosphorylation down-regulates ⊣ | BCL3 | 15469820 | SIGNOR-276011 |
| CHUK | phosphorylation up-regulates → | BCL3 PSer454 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277363 |
| IKBKB | phosphorylation up-regulates → | BCL3 PSer454 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277365 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → up-regulates activity | BCL3 | SIGNOR-277360 |
| MAPK1 | phosphorylation → up-regulates activity | BCL3 | SIGNOR-277361 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | BCL3 | SIGNOR-276012 |
| CHUK | phosphorylation → up-regulates activity | BCL3 | SIGNOR-277362 |
| AKT2 | phosphorylation → up-regulates quantity by stabilization | BCL3 | SIGNOR-277359 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | BCL3 | SIGNOR-277358 |
| IKBKB | phosphorylation → up-regulates activity | BCL3 | SIGNOR-277364 |
| GSK3A | phosphorylation down-regulates quantity by destabilization | BCL3 | SIGNOR-276011 |
| CHUK | phosphorylation → up-regulates activity | BCL3 | SIGNOR-277363 |
| IKBKB | phosphorylation → up-regulates activity | BCL3 | SIGNOR-277365 |
