Entity Details

Name CAST
ID P20810
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK2A1CASTSer655
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QDPIDALsGDLDSCPphosphorylation
up-regulates activity		29581866SIGNOR-277388
PRKACACASTSer133
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DKKKEKKsLTPAVPVphosphorylation
up-regulates activity		36984009SIGNOR-277839
BRSK1CASTSer45
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KSQSTKLsVVHEKKSphosphorylation
up-regulates activity		27626661SIGNOR-263051
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK2A1phosphorylation
up-regulates
→
CAST
PSer655		phosphorylation
up-regulates
→		CAST29581866SIGNOR-277388
PRKACAphosphorylation
up-regulates
→
CAST
PSer133		phosphorylation
up-regulates
→		CAST36984009SIGNOR-277839
BRSK1phosphorylation
up-regulates
→
CAST
PSer45		phosphorylation
up-regulates
→		CAST27626661SIGNOR-263051
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK2A1phosphorylation
→
up-regulates activity 		CASTSIGNOR-277388
PRKACAphosphorylation
→
up-regulates activity 		CASTSIGNOR-277839
BRSK1phosphorylation
→
up-regulates activity 		CASTSIGNOR-263051