Entity Details

Name CD247
ID P20963
Role substrate
Enzymatic Domains
ITAM 1 61-89
PROSITE-ProRule
ITAM 2 100-128
PROSITE-ProRule
ITAM 3 131-159
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN22CD247dephosphorylation
down-regulates
16461343SIGNOR-144337
LCKCD247phosphorylation
up-regulates
8626561SIGNOR-41361
PTPN22CD247dephosphorylation
down-regulates activity
16461343SIGNOR-248837
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN22dephosphorylation
img/direct_inhibition.png
down-regulates
CD247SIGNOR-144337
LCKphosphorylation

up-regulates
CD247SIGNOR-41361
PTPN22dephosphorylation

down-regulates activity
CD247SIGNOR-248837