Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK11B	EIF3F	Ser46	PAAAPASsSDPAAAA	phosphorylation down-regulates	12446680	SIGNOR-95762
CDK11B	EIF3F	Thr119	GAARVIGtLLGTVDK	phosphorylation unknown	19245811	SIGNOR-184185
CDK11B	EIF3F	Ser46	PAAAPASsSDPAAAA	phosphorylation up-regulates activity	19245811	SIGNOR-273133
CDK11B	EIF3F	Thr119	GAARVIGtLLGTVDK	phosphorylation up-regulates activity	19245811	SIGNOR-273131
CDK11B	PRPF4	–		phosphorylation up-regulates activity	11418604	SIGNOR-280208
CDK11B	SRSF1	–		phosphorylation up-regulates activity	25529026	SIGNOR-279499
CDK11B	RBM17	–		phosphorylation up-regulates activity	23519612	SIGNOR-279510
CDK11B	THRAP3	Ser243	ASAVSELsPRERSPA	phosphorylation up-regulates activity	34526909	SIGNOR-280209

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK11B	phosphorylation up-regulates →	EIF3F PSer46	phosphorylation down-regulates ⊣	EIF3F	12446680	SIGNOR-95762
CDK11B	phosphorylation up-regulates →	EIF3F PThr119	phosphorylation down-regulates ⊣	EIF3F	19245811	SIGNOR-184185
CDK11B	phosphorylation up-regulates →	EIF3F PSer46	phosphorylation up-regulates →	EIF3F	19245811	SIGNOR-273133
CDK11B	phosphorylation up-regulates →	EIF3F PThr119	phosphorylation up-regulates →	EIF3F	19245811	SIGNOR-273131
CDK11B	phosphorylation up-regulates →	THRAP3 PSer243	phosphorylation up-regulates →	THRAP3	34526909	SIGNOR-280209

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK11B	phosphorylation down-regulates	EIF3F	SIGNOR-95762
CDK11B	phosphorylation → unknown	EIF3F	SIGNOR-184185
CDK11B	phosphorylation → up-regulates activity	EIF3F	SIGNOR-273133
CDK11B	phosphorylation → up-regulates activity	EIF3F	SIGNOR-273131
CDK11B	phosphorylation → up-regulates activity	PRPF4	SIGNOR-280208
CDK11B	phosphorylation → up-regulates activity	SRSF1	SIGNOR-279499
CDK11B	phosphorylation → up-regulates activity	RBM17	SIGNOR-279510
CDK11B	phosphorylation → up-regulates activity	THRAP3	SIGNOR-280209