Entity Details

Name TBXA2R
ID P21731-2
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GRK2TBXA2RSer239AQQRPRDsEVEMMAQphosphorylation
down-regulates activity		16956790SIGNOR-274088
GRK3TBXA2RSer239AQQRPRDsEVEMMAQphosphorylation
down-regulates activity		16956790SIGNOR-274090
GRK2TBXA2RSer357RLPGSSDsRASASRAphosphorylation
down-regulates activity		16956790SIGNOR-274089
GRK3TBXA2RSer357RLPGSSDsRASASRAphosphorylation
down-regulates activity		16956790SIGNOR-274091
PRKCATBXA2RSer145FSRPAVAsQRRAWATphosphorylation
down-regulates activity		16956790SIGNOR-274092
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GRK2phosphorylation
up-regulates
→
TBXA2R
PSer239		phosphorylation
down-regulates
⊣		TBXA2R16956790SIGNOR-274088
GRK3phosphorylation
up-regulates
→
TBXA2R
PSer239		phosphorylation
down-regulates
⊣		TBXA2R16956790SIGNOR-274090
GRK2phosphorylation
up-regulates
→
TBXA2R
PSer357		phosphorylation
down-regulates
⊣		TBXA2R16956790SIGNOR-274089
GRK3phosphorylation
up-regulates
→
TBXA2R
PSer357		phosphorylation
down-regulates
⊣		TBXA2R16956790SIGNOR-274091
PRKCAphosphorylation
up-regulates
→
TBXA2R
PSer145		phosphorylation
down-regulates
⊣		TBXA2R16956790SIGNOR-274092
Regulator Mechanism/Effect Target SIGNOR-ID
GRK2phosphorylation
→
down-regulates activity 		TBXA2RSIGNOR-274088
GRK3phosphorylation
→
down-regulates activity 		TBXA2RSIGNOR-274090
GRK2phosphorylation
→
down-regulates activity 		TBXA2RSIGNOR-274089
GRK3phosphorylation
→
down-regulates activity 		TBXA2RSIGNOR-274091
PRKCAphosphorylation
→
down-regulates activity 		TBXA2RSIGNOR-274092