| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | KCNA3 | Tyr187 | FSEEIRFyQLGEEAM | phosphorylation up-regulates | 11812778 | SIGNOR-114641 |
| SRC | KCNA3 | Tyr499 | EGEEQSQyMHVGSCQ | phosphorylation up-regulates | 11812778 | SIGNOR-114645 |
| NTRK2 | KCNA3 | Tyr162 | SFDAILYyYQSGGRI | phosphorylation down-regulates | 19166614 | SIGNOR-183519 |
| NTRK2 | KCNA3 | Tyr163 | FDAILYYyQSGGRIR | phosphorylation down-regulates | 19166614 | SIGNOR-183523 |
| NTRK2 | KCNA3 | Tyr161 | PSFDAILyYYQSGGR | phosphorylation down-regulates | 19166614 | SIGNOR-183515 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | KCNA3 PTyr187 | phosphorylation up-regulates → | KCNA3 | 11812778 | SIGNOR-114641 |
| SRC | phosphorylation up-regulates → | KCNA3 PTyr499 | phosphorylation up-regulates → | KCNA3 | 11812778 | SIGNOR-114645 |
| NTRK2 | phosphorylation up-regulates → | KCNA3 PTyr162 | phosphorylation down-regulates ⊣ | KCNA3 | 19166614 | SIGNOR-183519 |
| NTRK2 | phosphorylation up-regulates → | KCNA3 PTyr163 | phosphorylation down-regulates ⊣ | KCNA3 | 19166614 | SIGNOR-183523 |
| NTRK2 | phosphorylation up-regulates → | KCNA3 PTyr161 | phosphorylation down-regulates ⊣ | KCNA3 | 19166614 | SIGNOR-183515 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates | KCNA3 | SIGNOR-114641 |
| SRC | phosphorylation → up-regulates | KCNA3 | SIGNOR-114645 |
| NTRK2 | phosphorylation down-regulates | KCNA3 | SIGNOR-183519 |
| NTRK2 | phosphorylation down-regulates | KCNA3 | SIGNOR-183523 |
| NTRK2 | phosphorylation down-regulates | KCNA3 | SIGNOR-183515 |
