Entity Details

Name FGFR4
ID P22455
Role substrate
Enzymatic Domains
Ig-like C2-type 1 22-118
Ig-like C2-type 2 152-240
Ig-like C2-type 3 249-349
Protein kinase 467-755
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FGFR4FGFR4Tyr642RGVHHIDyYKKTSNGphosphorylation
up-regulates		18670643SIGNOR-179776
FGFR4FGFR4Tyr754LLAVSEEyLDLRLTFphosphorylation
up-regulates activity		8576110SIGNOR-251140
FGFR4FGFR4Tyr643GVHHIDYyKKTSNGRphosphorylation
up-regulates		18670643SIGNOR-179780
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FGFR4phosphorylation
up-regulates
→
FGFR4
PTyr642		phosphorylation
up-regulates
→		FGFR418670643SIGNOR-179776
FGFR4phosphorylation
up-regulates
→
FGFR4
PTyr754		phosphorylation
up-regulates
→		FGFR48576110SIGNOR-251140
FGFR4phosphorylation
up-regulates
→
FGFR4
PTyr643		phosphorylation
up-regulates
→		FGFR418670643SIGNOR-179780
Regulator Mechanism/Effect Target SIGNOR-ID
FGFR4phosphorylation
→
up-regulates 		FGFR4SIGNOR-179776
FGFR4phosphorylation
→
up-regulates activity 		FGFR4SIGNOR-251140
FGFR4phosphorylation
→
up-regulates 		FGFR4SIGNOR-179780