Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
FGFR3	MAP3K7	–		phosphorylation up-regulates activity	24466111	SIGNOR-279176
FGFR3	FGFR3	Tyr770	LSAPFEQySPGGQDT	phosphorylation down-regulates activity	11294897	SIGNOR-106746
FGFR3	FGFR3	Tyr577	RRPPGLDySFDTCKP	phosphorylation up-regulates activity	11294897	SIGNOR-106726
FGFR3	FGFR3	Tyr647	RDVHNLDyYKKTTNG	phosphorylation up-regulates activity	11294897	SIGNOR-106730
FGFR3	FGFR3	Tyr648	DVHNLDYyKKTTNGR	phosphorylation up-regulates activity	11294897	SIGNOR-106734
FGFR3	FGFR3	Tyr724	ANCTHDLyMIMRECW	phosphorylation up-regulates activity	11294897	SIGNOR-106738
FGFR3	FGFR3	Tyr760	TVTSTDEyLDLSAPF	phosphorylation up-regulates activity	11294897	SIGNOR-106742
FGFR3	STAT3	Tyr705	DPGSAAPyLKTKFIC	phosphorylation up-regulates activity	10918587	SIGNOR-251139
FGFR3	STAT1	Tyr701	DGPKGTGyIKTELIS	phosphorylation up-regulates activity	10918587	SIGNOR-251138
FGFR3	PTEN	Tyr240	RREDKFMyFEFPQPL	phosphorylation unknown	22891331	SIGNOR-191797
FGFR3	GLO1	Tyr136	GIAVPDVySACKRFE	phosphorylation up-regulates activity	34838714	SIGNOR-276181
FGFR3	TET2	Tyr1902	TRISLVFyQHKSMNE	phosphorylation down-regulates quantity by destabilization	33097695	SIGNOR-277535
FGFR3	CILK1	Tyr15	RQLGDGTyGSVLLGR	phosphorylation down-regulates activity	30782830	SIGNOR-277436

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
FGFR3	phosphorylation up-regulates →	FGFR3 PTyr770	phosphorylation down-regulates ⊣	FGFR3	11294897	SIGNOR-106746
FGFR3	phosphorylation up-regulates →	FGFR3 PTyr577	phosphorylation up-regulates →	FGFR3	11294897	SIGNOR-106726
FGFR3	phosphorylation up-regulates →	FGFR3 PTyr647	phosphorylation up-regulates →	FGFR3	11294897	SIGNOR-106730
FGFR3	phosphorylation up-regulates →	FGFR3 PTyr648	phosphorylation up-regulates →	FGFR3	11294897	SIGNOR-106734
FGFR3	phosphorylation up-regulates →	FGFR3 PTyr724	phosphorylation up-regulates →	FGFR3	11294897	SIGNOR-106738
FGFR3	phosphorylation up-regulates →	FGFR3 PTyr760	phosphorylation up-regulates →	FGFR3	11294897	SIGNOR-106742
FGFR3	phosphorylation up-regulates →	STAT3 PTyr705	phosphorylation up-regulates →	STAT3	10918587	SIGNOR-251139
FGFR3	phosphorylation up-regulates →	STAT1 PTyr701	phosphorylation up-regulates →	STAT1	10918587	SIGNOR-251138
FGFR3	phosphorylation up-regulates →	PTEN PTyr240	phosphorylation down-regulates ⊣	PTEN	22891331	SIGNOR-191797
FGFR3	phosphorylation up-regulates →	GLO1 PTyr136	phosphorylation up-regulates →	GLO1	34838714	SIGNOR-276181
FGFR3	phosphorylation up-regulates →	TET2 PTyr1902	phosphorylation down-regulates ⊣	TET2	33097695	SIGNOR-277535
FGFR3	phosphorylation up-regulates →	CILK1 PTyr15	phosphorylation down-regulates ⊣	CILK1	30782830	SIGNOR-277436

Regulator	Mechanism/Effect	Target	SIGNOR-ID
FGFR3	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-279176
FGFR3	phosphorylation → down-regulates activity	FGFR3	SIGNOR-106746
FGFR3	phosphorylation → up-regulates activity	FGFR3	SIGNOR-106726
FGFR3	phosphorylation → up-regulates activity	FGFR3	SIGNOR-106730
FGFR3	phosphorylation → up-regulates activity	FGFR3	SIGNOR-106734
FGFR3	phosphorylation → up-regulates activity	FGFR3	SIGNOR-106738
FGFR3	phosphorylation → up-regulates activity	FGFR3	SIGNOR-106742
FGFR3	phosphorylation → up-regulates activity	STAT3	SIGNOR-251139
FGFR3	phosphorylation → up-regulates activity	STAT1	SIGNOR-251138
FGFR3	phosphorylation → unknown	PTEN	SIGNOR-191797
FGFR3	phosphorylation → up-regulates activity	GLO1	SIGNOR-276181
FGFR3	phosphorylation down-regulates quantity by destabilization	TET2	SIGNOR-277535
FGFR3	phosphorylation → down-regulates activity	CILK1	SIGNOR-277436