| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA3 | NR4A1 | Ser351 | GRRGRLPsKPKQPPD | phosphorylation unknown | 16223362 | SIGNOR-249295 |
| RPS6KA2 | NR4A1 | Ser351 | GRRGRLPsKPKQPPD | phosphorylation down-regulates activity | 11883936 | SIGNOR-249429 |
| AKT | NR4A1 | Ser351 | GRRGRLPsKPKQPPD | phosphorylation down-regulates activity | 11274386 | SIGNOR-105927 |
| RPS6KA5 | NR4A1 | Ser351 | GRRGRLPsKPKQPPD | phosphorylation unknown | 16223362 | SIGNOR-249296 |
| AKT1 | NR4A1 | Ser351 | GRRGRLPsKPKQPPD | phosphorylation down-regulates activity | 11274386 | SIGNOR-252466 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA3 | phosphorylation up-regulates → | NR4A1 PSer351 | phosphorylation down-regulates ⊣ | NR4A1 | 16223362 | SIGNOR-249295 |
| RPS6KA2 | phosphorylation up-regulates → | NR4A1 PSer351 | phosphorylation down-regulates ⊣ | NR4A1 | 11883936 | SIGNOR-249429 |
| AKT | phosphorylation up-regulates → | NR4A1 PSer351 | phosphorylation down-regulates ⊣ | NR4A1 | 11274386 | SIGNOR-105927 |
| RPS6KA5 | phosphorylation up-regulates → | NR4A1 PSer351 | phosphorylation down-regulates ⊣ | NR4A1 | 16223362 | SIGNOR-249296 |
| AKT1 | phosphorylation up-regulates → | NR4A1 PSer351 | phosphorylation down-regulates ⊣ | NR4A1 | 11274386 | SIGNOR-252466 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA3 | phosphorylation → unknown | NR4A1 | SIGNOR-249295 |
| RPS6KA2 | phosphorylation → down-regulates activity | NR4A1 | SIGNOR-249429 |
| AKT | phosphorylation → down-regulates activity | NR4A1 | SIGNOR-105927 |
| RPS6KA5 | phosphorylation → unknown | NR4A1 | SIGNOR-249296 |
| AKT1 | phosphorylation → down-regulates activity | NR4A1 | SIGNOR-252466 |
