| Name | SFPQ |
| ID | P23246 |
| Role | substrate |
| Enzymatic Domains |
RRM 1 297-369 PROSITE-ProRule
RRM 2 371-452 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3A | SFPQ | – | phosphorylation down-regulates | 20932480 | SIGNOR-168385 | |
| GSK3B | SFPQ | – | phosphorylation down-regulates | 20932480 | SIGNOR-168392 | |
| PTK6 | SFPQ | – | phosphorylation down-regulates activity | 19439179 | SIGNOR-279754 | |
| ALK | SFPQ | Tyr293 | RRPGEKTyTQRCRLF | phosphorylation down-regulates | 17537995 | SIGNOR-155298 |
| GSK3B | SFPQ | Thr687 | PRGMGPGtPAGYGRG | phosphorylation down-regulates | 20932480 | SIGNOR-168389 |
| GSK3A | SFPQ | Thr687 | PRGMGPGtPAGYGRG | phosphorylation down-regulates | 20932480 | SIGNOR-168382 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ALK | phosphorylation up-regulates → | SFPQ PTyr293 | phosphorylation down-regulates ⊣ | SFPQ | 17537995 | SIGNOR-155298 |
| GSK3B | phosphorylation up-regulates → | SFPQ PThr687 | phosphorylation down-regulates ⊣ | SFPQ | 20932480 | SIGNOR-168389 |
| GSK3A | phosphorylation up-regulates → | SFPQ PThr687 | phosphorylation down-regulates ⊣ | SFPQ | 20932480 | SIGNOR-168382 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3A | phosphorylation down-regulates | SFPQ | SIGNOR-168385 |
| GSK3B | phosphorylation down-regulates | SFPQ | SIGNOR-168392 |
| PTK6 | phosphorylation → down-regulates activity | SFPQ | SIGNOR-279754 |
| ALK | phosphorylation down-regulates | SFPQ | SIGNOR-155298 |
| GSK3B | phosphorylation down-regulates | SFPQ | SIGNOR-168389 |
| GSK3A | phosphorylation down-regulates | SFPQ | SIGNOR-168382 |