| Name | RPS3 |
| ID | P23396 |
| Role | substrate |
| Enzymatic Domains |
KH type-2 21-92 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | RPS3 | Ser6 | sKKRKFVA | phosphorylation up-regulates | 15950189 | SIGNOR-137967 |
| PPP2CA | RPS3 | Ser6 | sKKRKFVA | dephosphorylation down-regulates | 15950189 | SIGNOR-137963 |
| PRKCD | RPS3 | Thr221 | KDEILPTtPISEQKG | phosphorylation up-regulates | 19059439 | SIGNOR-182623 |
| PRKCD | RPS3 | Ser6 | sKKRKFVA | phosphorylation up-regulates | 19059439 | SIGNOR-182619 |
| MAPK1 | RPS3 | Thr42 | SGVEVRVtPTRTEII | phosphorylation unknown | 15950189 | SIGNOR-136075 |
| CDK1 | RPS3 | Thr221 | KDEILPTtPISEQKG | phosphorylation up-regulates | 21871177 | SIGNOR-176131 |
| Gbeta | RPS3 | – | phosphorylation unknown | 15950189 | SIGNOR-270019 | |
| IKBKB | RPS3 | Ser209 | KPLPDHVsIVEPKDE | phosphorylation up-regulates activity | 21399639 | SIGNOR-278360 |
| MAPK3 | RPS3 | Thr42 | SGVEVRVtPTRTEII | phosphorylation up-regulates | 15950189 | SIGNOR-137175 |
| AKT | RPS3 | Thr70 | GRRIRELtAVVQKRF | phosphorylation up-regulates activity | 20605787 | SIGNOR-259816 |
| AKT1 | RPS3 | Thr70 | GRRIRELtAVVQKRF | phosphorylation up-regulates activity | 20605787 | SIGNOR-259815 |
| MAPK3 | RPS3 | Thr42 | SGVEVRVtPTRTEII | phosphorylation unknown | 15950189 | SIGNOR-137959 |
| MAPK1 | RPS3 | Thr42 | SGVEVRVtPTRTEII | phosphorylation up-regulates | 15950189 | SIGNOR-137955 |
| PRKCD | RPS3 | Thr221 | KDEILPTtPISEQKG | phosphorylation up-regulates activity | 19059439 | SIGNOR-260895 |
| ERK1/2 | RPS3 | – | phosphorylation unknown | 15950189 | SIGNOR-270145 | |
| PRKCD | RPS3 | Ser6 | sKKRKFVA | phosphorylation up-regulates activity | 19059439 | SIGNOR-260894 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | phosphorylation up-regulates → | RPS3 PSer6 | phosphorylation up-regulates → | RPS3 | 15950189 | SIGNOR-137967 |
| PPP2CA | dephosphorylation down-regulates ⊣ | RPS3 PSer6 | dephosphorylation up-regulates → | RPS3 | 15950189 | SIGNOR-137963 |
| PRKCD | phosphorylation up-regulates → | RPS3 PThr221 | phosphorylation up-regulates → | RPS3 | 19059439 | SIGNOR-182623 |
| PRKCD | phosphorylation up-regulates → | RPS3 PSer6 | phosphorylation up-regulates → | RPS3 | 19059439 | SIGNOR-182619 |
| MAPK1 | phosphorylation up-regulates → | RPS3 PThr42 | phosphorylation down-regulates ⊣ | RPS3 | 15950189 | SIGNOR-136075 |
| CDK1 | phosphorylation up-regulates → | RPS3 PThr221 | phosphorylation up-regulates → | RPS3 | 21871177 | SIGNOR-176131 |
| IKBKB | phosphorylation up-regulates → | RPS3 PSer209 | phosphorylation up-regulates → | RPS3 | 21399639 | SIGNOR-278360 |
| MAPK3 | phosphorylation up-regulates → | RPS3 PThr42 | phosphorylation up-regulates → | RPS3 | 15950189 | SIGNOR-137175 |
| AKT | phosphorylation up-regulates → | RPS3 PThr70 | phosphorylation up-regulates → | RPS3 | 20605787 | SIGNOR-259816 |
| AKT1 | phosphorylation up-regulates → | RPS3 PThr70 | phosphorylation up-regulates → | RPS3 | 20605787 | SIGNOR-259815 |
| MAPK3 | phosphorylation up-regulates → | RPS3 PThr42 | phosphorylation down-regulates ⊣ | RPS3 | 15950189 | SIGNOR-137959 |
| MAPK1 | phosphorylation up-regulates → | RPS3 PThr42 | phosphorylation up-regulates → | RPS3 | 15950189 | SIGNOR-137955 |
| PRKCD | phosphorylation up-regulates → | RPS3 PThr221 | phosphorylation up-regulates → | RPS3 | 19059439 | SIGNOR-260895 |
| PRKCD | phosphorylation up-regulates → | RPS3 PSer6 | phosphorylation up-regulates → | RPS3 | 19059439 | SIGNOR-260894 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCD | phosphorylation → up-regulates | RPS3 | SIGNOR-137967 |
| PPP2CA | dephosphorylation down-regulates | RPS3 | SIGNOR-137963 |
| PRKCD | phosphorylation → up-regulates | RPS3 | SIGNOR-182623 |
| PRKCD | phosphorylation → up-regulates | RPS3 | SIGNOR-182619 |
| MAPK1 | phosphorylation → unknown | RPS3 | SIGNOR-136075 |
| CDK1 | phosphorylation → up-regulates | RPS3 | SIGNOR-176131 |
| Gbeta | phosphorylation → unknown | RPS3 | SIGNOR-270019 |
| IKBKB | phosphorylation → up-regulates activity | RPS3 | SIGNOR-278360 |
| MAPK3 | phosphorylation → up-regulates | RPS3 | SIGNOR-137175 |
| AKT | phosphorylation → up-regulates activity | RPS3 | SIGNOR-259816 |
| AKT1 | phosphorylation → up-regulates activity | RPS3 | SIGNOR-259815 |
| MAPK3 | phosphorylation → unknown | RPS3 | SIGNOR-137959 |
| MAPK1 | phosphorylation → up-regulates | RPS3 | SIGNOR-137955 |
| PRKCD | phosphorylation → up-regulates activity | RPS3 | SIGNOR-260895 |
| ERK1/2 | phosphorylation → unknown | RPS3 | SIGNOR-270145 |
| PRKCD | phosphorylation → up-regulates activity | RPS3 | SIGNOR-260894 |