Entity Details

Name MCC
ID P23508
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKDCMCCSer118
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SELRSELsQSQHEVNphosphorylation
up-regulates activity		21779472SIGNOR-273530
ATRMCCSer120
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LRSELSQsQHEVNEDphosphorylation
up-regulates activity		21779472SIGNOR-273515
ATRMCCSer118
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SELRSELsQSQHEVNphosphorylation
up-regulates activity		21779472SIGNOR-273514
PRKDCMCCSer120
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LRSELSQsQHEVNEDphosphorylation
up-regulates activity		21779472SIGNOR-273531
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKDCphosphorylation
up-regulates
→
MCC
PSer118		phosphorylation
up-regulates
→		MCC21779472SIGNOR-273530
ATRphosphorylation
up-regulates
→
MCC
PSer120		phosphorylation
up-regulates
→		MCC21779472SIGNOR-273515
ATRphosphorylation
up-regulates
→
MCC
PSer118		phosphorylation
up-regulates
→		MCC21779472SIGNOR-273514
PRKDCphosphorylation
up-regulates
→
MCC
PSer120		phosphorylation
up-regulates
→		MCC21779472SIGNOR-273531
Regulator Mechanism/Effect Target SIGNOR-ID
PRKDCphosphorylation
→
up-regulates activity 		MCCSIGNOR-273530
ATRphosphorylation
→
up-regulates activity 		MCCSIGNOR-273515
ATRphosphorylation
→
up-regulates activity 		MCCSIGNOR-273514
PRKDCphosphorylation
→
up-regulates activity 		MCCSIGNOR-273531