| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | ITPKA | Thr311 | EHAQRAVtKPRYMQW | phosphorylation up-regulates | 9155020 | SIGNOR-48387 |
| PRKACA | ITPKA | Ser121 | LQQPRRLsTSSVSST | phosphorylation up-regulates activity | 9374536 | SIGNOR-249994 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CAMK2A | phosphorylation up-regulates → | ITPKA PThr311 | phosphorylation up-regulates → | ITPKA | 9155020 | SIGNOR-48387 |
| PRKACA | phosphorylation up-regulates → | ITPKA PSer121 | phosphorylation up-regulates → | ITPKA | 9374536 | SIGNOR-249994 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CAMK2A | phosphorylation → up-regulates | ITPKA | SIGNOR-48387 |
| PRKACA | phosphorylation → up-regulates activity | ITPKA | SIGNOR-249994 |
