| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | GATA2 | Ser401 | QTRNRKMsNKSKKSK | phosphorylation down-regulates activity | 15837948 | SIGNOR-244271 |
| AKT1 | GATA2 | Ser401 | QTRNRKMsNKSKKSK | phosphorylation down-regulates | 15837948 | SIGNOR-135614 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | GATA2 PSer401 | phosphorylation down-regulates ⊣ | GATA2 | 15837948 | SIGNOR-244271 |
| AKT1 | phosphorylation up-regulates → | GATA2 PSer401 | phosphorylation down-regulates ⊣ | GATA2 | 15837948 | SIGNOR-135614 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation → down-regulates activity | GATA2 | SIGNOR-244271 |
| AKT1 | phosphorylation![]() down-regulates | GATA2 | SIGNOR-135614 |