Entity Details

Name CDK1_Thr176
ID P23769
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1GATA2Thr176HLFGFPPtPPKEVSPphosphorylation
down-regulates quantity by destabilization		25670854SIGNOR-276884
FBXW7GATA2Thr176HLFGFPPtPPKEVSPubiquitination
down-regulates quantity by destabilization		25670854SIGNOR-256005
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
GATA2
PThr176		phosphorylation
down-regulates
⊣		GATA225670854SIGNOR-276884
FBXW7ubiquitination
up-regulates
→
GATA2
PThr176		ubiquitination
down-regulates
⊣		GATA225670854SIGNOR-256005
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		GATA2SIGNOR-276884
FBXW7ubiquitination
img/direct_inhibition.png
down-regulates quantity by destabilization 		GATA2SIGNOR-256005