| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | GABRR1 | Ser444 | QRKSQRSsYVSMRID | phosphorylation unknown | 12175859 | SIGNOR-262755 |
| MAPK1 | GABRR1 | Ser435 | TLASERSsPQRKSQR | phosphorylation unknown | 12175859 | SIGNOR-262747 |
| PRKCA | GABRR1 | Ser443 | PQRKSQRsSYVSMRI | phosphorylation unknown | 12175859 | SIGNOR-262752 |
| PRKCA | GABRR1 | Ser440 | RSSPQRKsQRSSYVS | phosphorylation unknown | 12175859 | SIGNOR-262753 |
| PRKG1 | GABRR1 | Ser443 | PQRKSQRsSYVSMRI | phosphorylation unknown | 12175859 | SIGNOR-262756 |
| PRKG1 | GABRR1 | Ser444 | QRKSQRSsYVSMRID | phosphorylation unknown | 12175859 | SIGNOR-262757 |
| PRKCA | GABRR1 | Ser447 | SQRSSYVsMRIDTHA | phosphorylation unknown | 12175859 | SIGNOR-262754 |
| MAPK1 | GABRR1 | Thr394 | SGLPPPRtAMLDGNY | phosphorylation unknown | 12175859 | SIGNOR-262749 |
| MAPK1 | GABRR1 | Ser434 | LTLASERsSPQRKSQ | phosphorylation unknown | 12175859 | SIGNOR-262748 |
| PRKACA | GABRR1 | Ser444 | QRKSQRSsYVSMRID | phosphorylation unknown | 12175859 | SIGNOR-262750 |
| PRKACA | GABRR1 | Ser443 | PQRKSQRsSYVSMRI | phosphorylation unknown | 12175859 | SIGNOR-262751 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | GABRR1 PSer444 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262755 |
| MAPK1 | phosphorylation up-regulates → | GABRR1 PSer435 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262747 |
| PRKCA | phosphorylation up-regulates → | GABRR1 PSer443 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262752 |
| PRKCA | phosphorylation up-regulates → | GABRR1 PSer440 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262753 |
| PRKG1 | phosphorylation up-regulates → | GABRR1 PSer443 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262756 |
| PRKG1 | phosphorylation up-regulates → | GABRR1 PSer444 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262757 |
| PRKCA | phosphorylation up-regulates → | GABRR1 PSer447 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262754 |
| MAPK1 | phosphorylation up-regulates → | GABRR1 PThr394 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262749 |
| MAPK1 | phosphorylation up-regulates → | GABRR1 PSer434 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262748 |
| PRKACA | phosphorylation up-regulates → | GABRR1 PSer444 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262750 |
| PRKACA | phosphorylation up-regulates → | GABRR1 PSer443 | phosphorylation down-regulates ⊣ | GABRR1 | 12175859 | SIGNOR-262751 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → unknown | GABRR1 | SIGNOR-262755 |
| MAPK1 | phosphorylation → unknown | GABRR1 | SIGNOR-262747 |
| PRKCA | phosphorylation → unknown | GABRR1 | SIGNOR-262752 |
| PRKCA | phosphorylation → unknown | GABRR1 | SIGNOR-262753 |
| PRKG1 | phosphorylation → unknown | GABRR1 | SIGNOR-262756 |
| PRKG1 | phosphorylation → unknown | GABRR1 | SIGNOR-262757 |
| PRKCA | phosphorylation → unknown | GABRR1 | SIGNOR-262754 |
| MAPK1 | phosphorylation → unknown | GABRR1 | SIGNOR-262749 |
| MAPK1 | phosphorylation → unknown | GABRR1 | SIGNOR-262748 |
| PRKACA | phosphorylation → unknown | GABRR1 | SIGNOR-262750 |
| PRKACA | phosphorylation → unknown | GABRR1 | SIGNOR-262751 |
