Entity Details

Name FCAR
ID P24071
Role substrate
Enzymatic Domains
Ig-like C2-type 1 42-107
Ig-like C2-type 2 139-200
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP2CAFCARSer284LTFARTPsVCKdephosphorylation
up-regulates activity		30766540SIGNOR-264858
GSK3BFCARSer284LTFARTPsVCKphosphorylation
down-regulates activity		30766540SIGNOR-264857
GSK3AFCARSer284LTFARTPsVCKphosphorylation
down-regulates activity		30766540SIGNOR-264856
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP2CAdephosphorylation
down-regulates
⊣
FCAR
PSer284		dephosphorylation
down-regulates
⊣		FCAR30766540SIGNOR-264858
GSK3Bphosphorylation
up-regulates
→
FCAR
PSer284		phosphorylation
down-regulates
⊣		FCAR30766540SIGNOR-264857
GSK3Aphosphorylation
up-regulates
→
FCAR
PSer284		phosphorylation
down-regulates
⊣		FCAR30766540SIGNOR-264856
Regulator Mechanism/Effect Target SIGNOR-ID
PPP2CAdephosphorylation
→
up-regulates activity 		FCARSIGNOR-264858
GSK3Bphosphorylation
→
down-regulates activity 		FCARSIGNOR-264857
GSK3Aphosphorylation
→
down-regulates activity 		FCARSIGNOR-264856