Entity Details

Name CDK7_Ser1934
ID P24928
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3POLR2ASer1934SPTYSPTsPKGSTYSphosphorylation
down-regulates		14662762SIGNOR-120252
TFIIHPOLR2ASer1934SPTYSPTsPKGSTYSphosphorylation
down-regulates quantity by destabilization		14662762SIGNOR-269359
MAPK1POLR2ASer1934SPTYSPTsPKGSTYSphosphorylation
down-regulates		14662762SIGNOR-120160
CDK7POLR2ASer1934SPTYSPTsPKGSTYSphosphorylation
down-regulates		14662762SIGNOR-120072
TFIIHPOLR2ASer1934SPTYSPTsPKGSTYSphosphorylation
up-regulates activity		24746699SIGNOR-269386
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
POLR2A
PSer1934		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-120252
TFIIHphosphorylation
up-regulates
→
POLR2A
PSer1934		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-269359
MAPK1phosphorylation
up-regulates
→
POLR2A
PSer1934		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-120160
CDK7phosphorylation
up-regulates
→
POLR2A
PSer1934		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-120072
TFIIHphosphorylation
up-regulates
→
POLR2A
PSer1934		phosphorylation
up-regulates
→		POLR2A24746699SIGNOR-269386
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates 		POLR2ASIGNOR-120252
TFIIHphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		POLR2ASIGNOR-269359
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates 		POLR2ASIGNOR-120160
CDK7phosphorylation
img/direct_inhibition.png
down-regulates 		POLR2ASIGNOR-120072
TFIIHphosphorylation
→
up-regulates activity 		POLR2ASIGNOR-269386