Entity Details

Name CyclinK/CDK13_Ser1941
ID P24928
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK12POLR2ASer1941SPKGSTYsPTSPGYSphosphorylation
up-regulates		22012619SIGNOR-176837
CyclinK/CDK12POLR2ASer1941SPKGSTYsPTSPGYSphosphorylation
up-regulates activity		32917631SIGNOR-273084
CDK13POLR2ASer1941SPKGSTYsPTSPGYSphosphorylation
up-regulates activity		32917631SIGNOR-273034
CyclinK/CDK13POLR2ASer1941SPKGSTYsPTSPGYSphosphorylation
up-regulates activity		32917631SIGNOR-273059
CDK9POLR2ASer1941SPKGSTYsPTSPGYSphosphorylation
up-regulates		24385927SIGNOR-203604
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK12phosphorylation
up-regulates
→
POLR2A
PSer1941		phosphorylation
up-regulates
→		POLR2A22012619SIGNOR-176837
CyclinK/CDK12phosphorylation
up-regulates
→
POLR2A
PSer1941		phosphorylation
up-regulates
→		POLR2A32917631SIGNOR-273084
CDK13phosphorylation
up-regulates
→
POLR2A
PSer1941		phosphorylation
up-regulates
→		POLR2A32917631SIGNOR-273034
CyclinK/CDK13phosphorylation
up-regulates
→
POLR2A
PSer1941		phosphorylation
up-regulates
→		POLR2A32917631SIGNOR-273059
CDK9phosphorylation
up-regulates
→
POLR2A
PSer1941		phosphorylation
up-regulates
→		POLR2A24385927SIGNOR-203604
Regulator Mechanism/Effect Target SIGNOR-ID
CDK12phosphorylation
→
up-regulates 		POLR2ASIGNOR-176837
CyclinK/CDK12phosphorylation
→
up-regulates activity 		POLR2ASIGNOR-273084
CDK13phosphorylation
→
up-regulates activity 		POLR2ASIGNOR-273034
CyclinK/CDK13phosphorylation
→
up-regulates activity 		POLR2ASIGNOR-273059
CDK9phosphorylation
→
up-regulates 		POLR2ASIGNOR-203604