Entity Details

Name MAPK3_Ser1920
ID P24928
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TFIIHPOLR2ASer1920SPTYSPTsPKYSPTSphosphorylation
down-regulates quantity by destabilization		14662762SIGNOR-269335
MAPK1POLR2ASer1920SPTYSPTsPKYSPTSphosphorylation
down-regulates		14662762SIGNOR-120152
MAPK3POLR2ASer1920SPTYSPTsPKYSPTSphosphorylation
down-regulates		14662762SIGNOR-120244
TFIIHPOLR2ASer1920SPTYSPTsPKYSPTSphosphorylation
up-regulates activity		24746699SIGNOR-269366
CDK7POLR2ASer1920SPTYSPTsPKYSPTSphosphorylation
down-regulates		14662762SIGNOR-120064
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TFIIHphosphorylation
up-regulates
→
POLR2A
PSer1920		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-269335
MAPK1phosphorylation
up-regulates
→
POLR2A
PSer1920		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-120152
MAPK3phosphorylation
up-regulates
→
POLR2A
PSer1920		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-120244
TFIIHphosphorylation
up-regulates
→
POLR2A
PSer1920		phosphorylation
up-regulates
→		POLR2A24746699SIGNOR-269366
CDK7phosphorylation
up-regulates
→
POLR2A
PSer1920		phosphorylation
down-regulates
⊣		POLR2A14662762SIGNOR-120064
Regulator Mechanism/Effect Target SIGNOR-ID
TFIIHphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		POLR2ASIGNOR-269335
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates 		POLR2ASIGNOR-120152
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates 		POLR2ASIGNOR-120244
TFIIHphosphorylation
→
up-regulates activity 		POLR2ASIGNOR-269366
CDK7phosphorylation
img/direct_inhibition.png
down-regulates 		POLR2ASIGNOR-120064