| Name | CDK2 |
| ID | P24941 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 4-286 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | FOXO | – | phosphorylation down-regulates | 19188143 | SIGNOR-252891 | |
| CDK2 | BRCA1 | Ser1497 | EPGVERSsPSKCPSL | phosphorylation up-regulates | 10550055 | SIGNOR-72091 |
| CDK2 | NPM1 | Thr234 | SFKKQEKtPKTPKGP | phosphorylation down-regulates activity | 11278991 | SIGNOR-235725 |
| CDK2 | RUNX1 | Ser276 | VHPATPIsPGRASGM | phosphorylation down-regulates activity | 17015473 | SIGNOR-149976 |
| CDK2 | SF3B1 | Thr244 | GRAKGSEtPGATPGS | phosphorylation up-regulates | 12105215 | SIGNOR-90434 |
| CDK2 | RBL2 | Ser639 | DEICIAGsPLTPRRV | phosphorylation unknown | 11157749 | SIGNOR-104679 |
| CDK2 | CDK7 | Thr170 | GSPNRAYtHQVVTRW | phosphorylation up-regulates | 11113184 | SIGNOR-85013 |
| CDK2 | RAD54L | Ser49 | QIQECFLsPFRKPLS | phosphorylation down-regulates activity | 29295984 | SIGNOR-273599 |
| CDK2 | SF3B1 | Thr248 | GSETPGAtPGSKIWD | phosphorylation up-regulates | 12105215 | SIGNOR-90438 |
| CDK2 | MYBL2 | Thr487 | SQKVVVTtPLHRDKT | phosphorylation up-regulates | 9840932 | SIGNOR-62361 |
| CDK2 | NBN | Ser432 | RIPNYQLsPTKLPSI | phosphorylation up-regulates activity | 22927831 | SIGNOR-279500 |
| CDK2 | APP | Thr743 | VEVDAAVtPEERHLS | phosphorylation down-regulates quantity by destabilization | 30881282 | SIGNOR-280210 |
| CDK2 | BARD1 | – | phosphorylation down-regulates activity | 15665273 | SIGNOR-280211 | |
| CDK2 | TTK | Thr468 | DYMSCFRtPVVKNDF | phosphorylation up-regulates quantity by stabilization | 20861309 | SIGNOR-279398 |
| CDK2 | PTPN2 | Ser304 | LSPAFDHsPNKIMTE | phosphorylation unknown | 15030318 | SIGNOR-123471 |
| CDK2 | CDC6 | Ser106 | DNQLTIKsPSKRELA | phosphorylation up-regulates | 10339564 | SIGNOR-67540 |
| CDK2 | RBL2 | Ser413 | VRYIKENsPCVTPVS | phosphorylation unknown | 11157749 | SIGNOR-104675 |
| CDK2 | CCNA2 | Ser154 | PMDGSFEsPHTMDMS | phosphorylation up-regulates | 10652300 | SIGNOR-74466 |
| CDK2 | CCP110 | Ser400 | PINACELsPKGKEQA | phosphorylation down-regulates activity | 12361598 | SIGNOR-265956 |
| CDK2 | MYBL2 | Thr266 | TDLDAVRtPEPLEEF | phosphorylation up-regulates activity | 10593981 | SIGNOR-250736 |
| CDK2 | MCM3 | Thr722 | EEMPQVHtPKTADSQ | phosphorylation up-regulates | 21965652 | SIGNOR-176656 |
| CDK2 | CDC6 | Ser74 | TPHLPPCsPPKQGKK | phosphorylation down-regulates activity | 10339564 | SIGNOR-67548 |
| CDK2 | BCL2L1 | Ser73 | NGATGHSsSLDAREV | phosphorylation up-regulates activity | 27239332 | SIGNOR-278242 |
| CDK2 | MCM4 | Thr19 | GSRRGRAtPAQTPRS | phosphorylation down-regulates activity | 12714602 | SIGNOR-100893 |
| CDK2 | UBTF | Ser389 | INKKQATsPASKKPA | phosphorylation up-regulates activity | 11698641 | SIGNOR-235419 |
| CDK2 | CDH1 | – | phosphorylation down-regulates activity | 23972993 | SIGNOR-279512 | |
| CDK2 | TK1 | Ser13 | LPTVLPGsPSKTRGQ | phosphorylation down-regulates | 14697231 | SIGNOR-120372 |
| CDK2 | RBL2 | Ser1112 | LLEDGSEsPAKRICP | phosphorylation down-regulates | 12006580 | SIGNOR-87492 |
| CDK2 | NR3C1 | Ser211 | PGKETNEsPWRSDLL | phosphorylation up-regulates activity | 9199329 | SIGNOR-249427 |
| CDK2 | NFYA | Ser326 | FSPKEKDsPHMQDPN | phosphorylation up-regulates activity | 12857729 | SIGNOR-250743 |
| CDK2 | RBL2 | Thr417 | KENSPCVtPVSTATH | phosphorylation unknown | 11157749 | SIGNOR-104699 |
| CDK2 | SMAD3 | Ser204 | NHSMDAGsPNLSPNP | phosphorylation unknown | 15241418 | SIGNOR-250749 |
| CDK2 | PLK1 | Thr210 | YDGERKKtLCGTPNY | phosphorylation up-regulates activity | 33402344 | SIGNOR-280212 |
| CDK2 | NCOR2 | – | phosphorylation down-regulates activity | 18838553 | SIGNOR-278306 | |
| CDK2 | ING5 | Thr152 | RRTSEEDtPKKKKHK | phosphorylation up-regulates quantity | 25860957 | SIGNOR-279447 |
| CDK2 | LIG1 | Ser91 | ALDCSQVsPPRPATS | phosphorylation up-regulates activity | 12851383 | SIGNOR-103254 |
| CDK2 | CROCC | Ser1460 | APRPVPGsPARDAPA | phosphorylation down-regulates | 22610972 | SIGNOR-197593 |
| CDK2 | CDKN1A | Ser130 | SGEQAEGsPGGPGDS | phosphorylation down-regulates quantity by destabilization | 15964852 | SIGNOR-149416 |
| CDK2 | GRK2 | Ser670 | KMKNKPRsPVVELSK | phosphorylation down-regulates | 20080565 | SIGNOR-163279 |
| CDK2 | TP63 | Thr491 | PQQRNALtPTTIPDG | phosphorylation down-regulates | 18769144 | SIGNOR-180767 |
| CDK2 | RBL2 | Ser952 | DSRSHQNsPTELNKD | phosphorylation unknown | 11157749 | SIGNOR-104691 |
| CDK2 | CCP110 | Thr566 | NTRQQMDtPMVSCGN | phosphorylation down-regulates activity | 12361598 | SIGNOR-265959 |
| CDK2 | MCM2 | Ser13 | ESFTMASsPAQRRRG | phosphorylation up-regulates | 16446360 | SIGNOR-144000 |
| CDK2 | NPM1 | Thr234 | SFKKQEKtPKTPKGP | phosphorylation down-regulates activity | 12058066 | SIGNOR-89609 |
| CDK2 | SP1 | Ser59 | GGQESQPsPLALLAA | phosphorylation up-regulates activity | 11598016 | SIGNOR-248232 |
| CDK2 | FOXK2 | Ser428 | FAQSAPGsPLSSQPV | phosphorylation up-regulates | 20810654 | SIGNOR-167834 |
| CDK2 | MYOD1 | Ser200 | YSGDSDAsSPRSNCS | phosphorylation down-regulates | 21902831 | SIGNOR-176509 |
| CDK2 | CDK7 | Ser164 | GLAKSFGsPNRAYTH | phosphorylation unknown | 11113184 | SIGNOR-84832 |
| CDK2 | PARP1 | – | phosphorylation up-regulates activity | 22948662 | SIGNOR-279146 | |
| CDK2 | ARID4A | Ser864 | RKILGQSsPEKKIRI | phosphorylation down-regulates | 21148318 | SIGNOR-170455 |
| CDK2 | RBL2 | Thr694 | DSPSDGGtPGRMPPQ | phosphorylation unknown | 11157749 | SIGNOR-104707 |
| CDK2 | RB1 | – | phosphorylation down-regulates | 21902831 | SIGNOR-176512 | |
| CDK2 | ESR1 | Ser106 | PLNSVSPsPLMLLHP | phosphorylation up-regulates | 10428798 | SIGNOR-69714 |
| CDK2 | MYBL2 | Thr515 | QKYSMDNtPHTPTPF | phosphorylation up-regulates activity | 10593981 | SIGNOR-250739 |
| CDK2 | LARP1 | – | phosphorylation up-regulates activity | 34449924 | SIGNOR-279015 | |
| CDK2 | SKP2 | Ser64 | SNLGHPEsPPRKRLK | phosphorylation up-regulates quantity by stabilization | 18239684 | SIGNOR-249173 |
| CDK2 | SMAD3 | Thr8 | MSSILPFtPPIVKRL | phosphorylation down-regulates | 19114991 | SIGNOR-182975 |
| CDK2 | PTPN12 | Ser19 | QRVQAMKsPDHNGED | phosphorylation down-regulates activity | 28842430 | SIGNOR-277366 |
| CDK2 | ATRIP | Ser224 | APSVSHVsPRKNPSV | phosphorylation up-regulates | 17638878 | SIGNOR-156928 |
| CDK2 | RBL2 | Thr1097 | SMIRTGEtPTKKRGI | phosphorylation unknown | 11157749 | SIGNOR-104695 |
| CDK2 | CCP110 | Ser170 | RDSEGFNsPKQCDSS | phosphorylation down-regulates activity | 12361598 | SIGNOR-265958 |
| CDK2 | CDKN2D | Thr141 | RRDARGLtPLELALQ | phosphorylation up-regulates | 22558186 | SIGNOR-197274 |
| CDK2 | CCDC6 | Ser244 | QPVSAPPsPRDISME | phosphorylation up-regulates | 14712216 | SIGNOR-121198 |
| CDK2 | ID3 | Ser5 | sPVRGCYE | phosphorylation down-regulates | 9372912 | SIGNOR-53306 |
| CDK2 | POLL | Thr553 | GPGRVLPtPTEKDVF | phosphorylation up-regulates quantity by stabilization | 18688254 | SIGNOR-276169 |
| CDK2 | MYC | Ser62 | S-->E | phosphorylation up-regulates quantity by stabilization | 35039060 | SIGNOR-279808 |
| CDK2 | CDH1 | Thr40 | DAESYTFtVPRRHLE | phosphorylation down-regulates quantity by destabilization | 23972993 | SIGNOR-274050 |
| CDK2 | PPP1CA | Thr320 | NPGGRPItPPRNSAK | phosphorylation down-regulates activity | 12202491 | SIGNOR-92265 |
| CDK2 | CCP110 | Thr194 | FPKTSSAtPQETLIS | phosphorylation down-regulates activity | 12361598 | SIGNOR-265961 |
| CDK2 | RECQL4 | Ser251 | EVSIRVGsPQPSSSG | phosphorylation up-regulates activity | 29229926 | SIGNOR-277374 |
| CDK2 | SF3B1 | Thr313 | HGSGWAEtPRTDRGG | phosphorylation unknown | 12105215 | SIGNOR-90442 |
| CDK2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 22369944 | SIGNOR-196372 |
| CDK2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 17601773 | SIGNOR-156509 |
| CDK2 | FOXO1 | Ser249 | EGGKSGKsPRRRAAS | phosphorylation down-regulates | 17038621 | SIGNOR-150028 |
| CDK2 | FOXO4 | – | phosphorylation down-regulates | 19188143 | SIGNOR-183655 | |
| CDK2 | MYBL2 | Thr518 | SMDNTPHtPTPFKNA | phosphorylation up-regulates activity | 10593981 | SIGNOR-250740 |
| CDK2 | MYBL2 | Thr440 | LDSCNSLtPKSTPVK | phosphorylation unknown | 10095772 | SIGNOR-250738 |
| CDK2 | SOX2 | Ser37 | AGGNQKNsPDRVKRP | phosphorylation up-regulates activity | 26139602 | SIGNOR-279448 |
| CDK2 | SOX2 | Ser251 | VKSEASSsPPVVTSS | phosphorylation up-regulates activity | 26139602 | SIGNOR-279449 |
| CDK2 | POLL | – | phosphorylation up-regulates activity | 16174846 | SIGNOR-278919 | |
| CDK2 | TOB2 | Ser254 | PAPQSQLsPNAKEFV | phosphorylation up-regulates activity | 32404348 | SIGNOR-273601 |
| CDK2 | BRCA1 | Ser1497 | EPGVERSsPSKCPSL | phosphorylation up-regulates | 19683496 | SIGNOR-187607 |
| CDK2 | NPAT | Thr1270 | SDLPVPRtPGSGAGE | phosphorylation up-regulates | 10995387 | SIGNOR-82137 |
| CDK2 | ARID4A | Ser1007 | QHNFSVAsPLTLSQD | phosphorylation down-regulates | 21148318 | SIGNOR-170451 |
| CDK2 | NR3C1 | Ser203 | DLEFSSGsPGKETNE | phosphorylation up-regulates activity | 9199329 | SIGNOR-249426 |
| CDK2 | ZBTB16 | Thr282 | RGKEGPGtPTRSSVI | phosphorylation down-regulates | 18246121 | SIGNOR-160630 |
| CDK2 | CCP110 | Ser516 | ASSQCIAsPNFGTVS | phosphorylation down-regulates activity | 12361598 | SIGNOR-265963 |
| CDK2 | CDH1 | Ser36 | HPGFDAEsYTFTVPR | phosphorylation down-regulates quantity by destabilization | 23972993 | SIGNOR-274049 |
| CDK2 | ELK4 | Thr194 | SVIKFVTtPSKKPPV | phosphorylation up-regulates activity | 26028036 | SIGNOR-278211 |
| CDK2 | MYBL2 | Ser393 | RGELIPIsPSTEVGG | phosphorylation up-regulates activity | 10593981 | SIGNOR-250734 |
| CDK2 | WEE1 | Ser123 | EEGFGSSsPVKSPAA | phosphorylation down-regulates | 16085715 | SIGNOR-139469 |
| CDK2 | LIG1 | Ser76 | EEEDEALsPAKGQKP | phosphorylation up-regulates activity | 12851383 | SIGNOR-103250 |
| CDK2 | MCM4 | Ser54 | ELQPMPTsPGVDLQS | phosphorylation down-regulates activity | 12714602 | SIGNOR-100885 |
| CDK2 | MECOM | Ser624 | KMFKDKVsPLQNLAS | phosphorylation up-regulates activity | 33082307 | SIGNOR-273426 |
| CDK2 | RUNX1 | Ser276 | VHPATPIsPGRASGM | phosphorylation up-regulates activity | 16046550 | SIGNOR-138936 |
| CDK2 | NPAT | Thr1350 | ISRTTSAtPLKDNTQ | phosphorylation up-regulates | 10995387 | SIGNOR-82141 |
| CDK2 | CDC6 | Ser54 | RVKALPLsPRKRLGD | phosphorylation down-regulates activity | 10339564 | SIGNOR-67544 |
| CDK2 | PRDX1 | Thr90 | CHLAWVNtPKKQGGL | phosphorylation down-regulates | 11986303 | SIGNOR-87101 |
| CDK2 | RBL2 | Ser688 | RLFVENDsPSDGGTP | phosphorylation unknown | 11157749 | SIGNOR-104687 |
| CDK2 | CCP110 | Ser45 | FHGVAILsPLLNIEK | phosphorylation down-regulates activity | 12361598 | SIGNOR-265957 |
| CDK2 | DLG1 | Ser443 | FLGQTPAsPARYSPV | phosphorylation up-regulates | 19066288 | SIGNOR-182765 |
| CDK2 | ZC3HC1 | Ser395 | PGLEVPSsPLRKAKR | phosphorylation down-regulates | 17389604 | SIGNOR-154051 |
| CDK2 | TFCP2 | Ser309 | SLGEGNGsPNHQPEP | phosphorylation down-regulates | 19237534 | SIGNOR-184160 |
| CDK2 | NFYA | Ser320 | GEGGRFFsPKEKDSP | phosphorylation up-regulates activity | 12857729 | SIGNOR-250742 |
| CDK2 | CCP110 | Ser372 | PSPEPSMsPKMHRRR | phosphorylation down-regulates activity | 12361598 | SIGNOR-265962 |
| CDK2 | RAD9A | Ser328 | VLPSISLsPGPQPPK | phosphorylation unknown | 23028682 | SIGNOR-199020 |
| CDK2 | ORC2 | Thr116 | LASELAKtPQKSVSF | phosphorylation up-regulates | 11931757 | SIGNOR-116364 |
| CDK2 | RBL2 | Ser1068 | HKNETMLsPREKIFY | phosphorylation unknown | 11157749 | SIGNOR-104667 |
| CDK2 | FZR1 | Ser163 | KSQKLLRsPRKPTRK | phosphorylation down-regulates activity | 12560341 | SIGNOR-250733 |
| CDK2 | ORC2 | Thr226 | SAPVGKEtPSKRMKR | phosphorylation up-regulates | 11931757 | SIGNOR-116476 |
| CDK2 | EZH2 | Thr416 | EANSRCQtPIKMKPN | phosphorylation up-regulates activity | 23241245 | SIGNOR-255656 |
| CDK2 | FOXO | Ser249 | EGGKSGKsPRRRAAS | phosphorylation down-regulates | 17038621 | SIGNOR-252892 |
| CDK2 | SIRT1 | Ser47 | DGPGLERsPGEPGGA | phosphorylation up-regulates activity | 27991597 | SIGNOR-279513 |
| CDK2 | MYBL2 | Thr494 | TPLHRDKtPLHQKHA | phosphorylation up-regulates | 9840932 | SIGNOR-62365 |
| CDK2 | CDC20 | – | phosphorylation down-regulates activity | 26960431 | SIGNOR-279322 | |
| CDK2 | FZR1 | Ser151 | DVSPYSLsPVSNKSQ | phosphorylation down-regulates activity | 12560341 | SIGNOR-250732 |
| CDK2 | TK1 | Ser13 | LPTVLPGsPSKTRGQ | phosphorylation down-regulates | 12435275 | SIGNOR-95578 |
| CDK2 | COIL | Ser184 | NEEAKRKsPKKKEKC | phosphorylation up-regulates | 11102515 | SIGNOR-84949 |
| CDK2 | CDX2 | Ser295 | LQASVPGsVPGVLGP | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250730 |
| CDK2 | RBL2 | Ser662 | GLGRSITsPTTLYDR | phosphorylation unknown | 11157749 | SIGNOR-104683 |
| CDK2 | PP1 | – | phosphorylation down-regulates activity | 12202491 | SIGNOR-264650 | |
| CDK2 | CDKN2D | Ser76 | VQDTSGTsPVHDAAR | phosphorylation up-regulates | 22558186 | SIGNOR-197270 |
| CDK2 | ID2 | Ser5 | sPVRSVRK | phosphorylation down-regulates | 9029153 | SIGNOR-46397 |
| CDK2 | TP53 | Ser315 | LPNNTSSsPQPKKKP | phosphorylation up-regulates activity | 24173284 | SIGNOR-119379 |
| CDK2 | CDX2 | Ser291 | PVSSLQAsVPGSVPG | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250729 |
| CDK2 | PGR | Thr430 | PPLPPRAtPSRPGEA | phosphorylation unknown | 11110801 | SIGNOR-85000 |
| CDK2 | PGR | Ser20 | HVAGGPPsPEVGSPL | phosphorylation unknown | 11110801 | SIGNOR-84980 |
| CDK2 | SMAD3 | Ser213 | NLSPNPMsPAHNNLD | phosphorylation down-regulates | 15241418 | SIGNOR-126732 |
| CDK2 | SMAD3 | Thr179 | PQSNIPEtPPPGYLS | phosphorylation down-regulates activity | 15241418 | SIGNOR-126736 |
| CDK2 | FOXM1 | Thr611 | ETLPISStPSKSVLP | phosphorylation up-regulates activity | 15024056 | SIGNOR-250731 |
| CDK2 | HMGA1 | Ser36 | PRKQPPVsPGTALVG | phosphorylation down-regulates | 17960875 | SIGNOR-158612 |
| CDK2 | SMAD3 | Thr8 | MSSILPFtPPIVKRL | phosphorylation down-regulates activity | 15241418 | SIGNOR-217734 |
| CDK2 | CDX2 | Ser287 | EPLSPVSsLQASVPG | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-250728 |
| CDK2 | MAP3K11 | Ser770 | LISRPRPsPLRSRID | phosphorylation up-regulates activity | 35843311 | SIGNOR-277604 |
| CDK2 | PTPN6 | – | phosphorylation down-regulates quantity by destabilization | 18617527 | SIGNOR-279147 | |
| CDK2 | DNMT1 | Ser154 | AKPEPSPsPRITRKS | phosphorylation up-regulates | 21565170 | SIGNOR-173681 |
| CDK2 | PGR | Ser213 | SGAPVKPsPQAAAVE | phosphorylation unknown | 11110801 | SIGNOR-84984 |
| CDK2 | ESR1 | Ser104 | FPPLNSVsPSPLMLL | phosphorylation up-regulates | 10428798 | SIGNOR-69710 |
| CDK2 | CHEK1 | Ser301 | IQSNLDFsPVNSASS | phosphorylation up-regulates | 21765472 | SIGNOR-175083 |
| CDK2 | TPX2 | Thr72 | NLQQAIVtPLKPVDN | phosphorylation down-regulates activity | 25688093 | SIGNOR-265099 |
| CDK2 | RUNX1 | Ser249 | DTRQIQPsPPWSYDQ | phosphorylation up-regulates activity | 16046550 | SIGNOR-138928 |
| CDK2 | CDK2 | Thr160 | GVPVRTYtHEVVTLW | phosphorylation up-regulates | 17361108 | SIGNOR-153636 |
| CDK2 | KLF10 | Ser206 | NIPCAAVsPNRSKCE | phosphorylation up-regulates quantity | 25728284 | SIGNOR-278394 |
| CDK2 | CDC25C | Ser214 | SRSGLYRsPSMPENL | phosphorylation up-regulates | 20530684 | SIGNOR-165872 |
| CDK2 | HIRA | Thr555 | LSPSVLTtPSKIEPM | phosphorylation up-regulates activity | 11238922 | SIGNOR-105548 |
| CDK2 | RBL2 | Thr642 | CIAGSPLtPRRVTEV | phosphorylation unknown | 11157749 | SIGNOR-104703 |
| CDK2 | PTHLH | Thr121 | YKEQPLKtPGKKKKG | phosphorylation down-regulates | 10373465 | SIGNOR-68548 |
| CDK2 | NPM1 | Ser70 | EAMNYEGsPIKVTLA | phosphorylation unknown | 19933706 | SIGNOR-161805 |
| CDK2 | RUNX1 | Thr273 | SPSVHPAtPISPGRA | phosphorylation up-regulates activity | 16046550 | SIGNOR-138940 |
| CDK2 | CCP110 | Ser366 | GSYAKLPsPEPSMSP | phosphorylation down-regulates activity | 12361598 | SIGNOR-265960 |
| CDK2 | ESR1 | Ser118 | LHPPPQLsPFLQPHG | phosphorylation up-regulates | 10428798 | SIGNOR-69718 |
| CDK2 | PELP1 | Ser991 | PALPPPEsPPKVQPE | phosphorylation up-regulates | 20807815 | SIGNOR-167766 |
| CDK2 | MCM4 | Thr110 | PRSGVRGtPVRQRPD | phosphorylation down-regulates activity | 12714602 | SIGNOR-100889 |
| CDK2 | RBL2 | Ser1080 | IFYYFSNsPSKRLRE | phosphorylation unknown | 11157749 | SIGNOR-104671 |
| CDK2 | SIRT2 | Ser368 | PNPSTSAsPKKSPPP | phosphorylation down-regulates | 18332217 | SIGNOR-177972 |
| CDK2 | MYBL2 | Ser577 | RKPGLRRsPIKKVRK | phosphorylation up-regulates | 9840932 | SIGNOR-62353 |
| CDK2 | TP63 | Ser560 | LARLGCSsCLDYFTT | phosphorylation down-regulates | 18769144 | SIGNOR-180763 |
| CDK2 | TP73 | Thr86 | AASASPYtPEHAASV | phosphorylation down-regulates activity | 12676926 | SIGNOR-99746 |
| CDK2 | TP63 | Ser477 | NSMNKLPsVSQLINP | phosphorylation down-regulates | 18769144 | SIGNOR-180759 |
| CDK2 | RRN3 | Ser44 | LENDFFNsPPRKTVR | phosphorylation up-regulates | 15004009 | SIGNOR-123231 |
| CDK2 | CHEK1 | Ser286 | TSGGVSEsPSGFSKH | phosphorylation up-regulates | 21765472 | SIGNOR-175079 |
| CDK2 | MYBL2 | Thr405 | VGGSGIGtPPSVLKR | phosphorylation up-regulates activity | 10593981 | SIGNOR-250737 |
| CDK2 | LIG3 | Ser210 | TTTGQVTsPVKGASF | phosphorylation down-regulates | 17040896 | SIGNOR-150121 |
| CDK2 | SMAD2 | Thr8 | MSSILPFtPPVVKRL | phosphorylation down-regulates activity | 19201832 | SIGNOR-279678 |
| CDK2 | MYBL2 | Thr520 | DNTPHTPtPFKNALE | phosphorylation up-regulates activity | 10593981 | SIGNOR-250741 |
| CDK2 | SMAD3 | Ser213 | NLSPNPMsPAHNNLD | phosphorylation down-regulates | 19114991 | SIGNOR-182967 |
| CDK2 | CCNE1 | Ser399 | GLLTPPQsGKKQSSG | phosphorylation down-regulates | 14536078 | SIGNOR-118555 |
| CDK2 | RAD51 | – | phosphorylation down-regulates quantity by destabilization | 25927241 | SIGNOR-280213 | |
| CDK2 | RNF138 | Thr27 | VCQEVLKtPVRTTAC | phosphorylation up-regulates activity | 38309501 | SIGNOR-277831 |
| CDK2 | SMAD3 | Thr8 | MSSILPFtPPIVKRL | phosphorylation down-regulates | 15241418 | SIGNOR-126740 |
| CDK2 | LIG1 | Ser51 | GVVSESDsPVKRPGR | phosphorylation up-regulates activity | 12851383 | SIGNOR-103246 |
| CDK2 | CDX2 | Ser283 | RSVPEPLsPVSSLQA | phosphorylation down-regulates quantity by destabilization | 16027724 | SIGNOR-138825 |
| CDK2 | NR1I2 | Ser350 | MQAISLFsPDRPGVL | phosphorylation down-regulates quantity by destabilization | 35053380 | SIGNOR-279397 |
| CDK2 | RPL12 | Ser38 | KIGPLGLsPKKVGDD | phosphorylation unknown | 18847512 | SIGNOR-181603 |
| CDK2 | SMAD3 | Ser213 | NLSPNPMsPAHNNLD | phosphorylation down-regulates activity | 15241418 | SIGNOR-232134 |
| CDK2 | MCM3AP | Ser508 | FWHRKKIsPNKKPFS | phosphorylation up-regulates activity | 11526238 | SIGNOR-262734 |
| CDK2 | RNF4 | Thr112 | DVYVTTHtPRNARDE | phosphorylation up-regulates activity | 25948581 | SIGNOR-276901 |
| CDK2 | UHRF1 | Ser675 | KTKVEPYsLTAQQSS | phosphorylation down-regulates quantity by destabilization | 26727879 | SIGNOR-277192 |
| CDK2 | ZBTB16 | Ser197 | SFGLSAMsPTKAAVD | phosphorylation down-regulates | 18246121 | SIGNOR-160626 |
| CDK2 | CCNO | Ser81 | PSAARGGsPLPGPAQ | phosphorylation up-regulates activity | 25364462 | SIGNOR-275615 |
| CDK2 | MYBL2 | Ser452 | PVKTLPFsPSQFLNF | phosphorylation up-regulates activity | 10593981 | SIGNOR-250735 |
| CDK2 | GATA3 | Thr156 | HLFTFPPtPPKDVSP | phosphorylation down-regulates quantity by destabilization | 24820417 | SIGNOR-276634 |
| CDK2 | RNF157 | – | phosphorylation up-regulates activity | 28655764 | SIGNOR-279016 | |
| CDK2 | PGR | Ser294 | APMAPGRsPLATTVM | phosphorylation down-regulates | 10655479 | SIGNOR-74708 |
| CDK2 | RBL2 | Ser1044 | YPFVRTGsPRRIQLS | phosphorylation unknown | 11157749 | SIGNOR-104660 |
| CDK2 | MYBL2 | Thr444 | NSLTPKStPVKTLPF | phosphorylation up-regulates | 9840932 | SIGNOR-62357 |
| CDK2 | SMAD3 | Ser208 | DAGSPNLsPNPMSPA | phosphorylation unknown | 15241418 | SIGNOR-250750 |
| CDK2 | PGR | Ser554 | PDSEASQsPQYSFES | phosphorylation unknown | 11110801 | SIGNOR-84992 |
| CDK2 | RB1 | Thr821 | KISEGLPtPTKMTPR | phosphorylation down-regulates | 9139732 | SIGNOR-47895 |
| CDK2 | CDC6 | Ser54 | RVKALPLsPRKRLGD | phosphorylation down-regulates activity | 9889196 | SIGNOR-63891 |
| CDK2 | CDC25A | Ser263 | CKLFDSPsLCSSSTR | phosphorylation down-regulates | 17110335 | SIGNOR-150839 |
| CDK2 | CCNE1 | Thr395 | PLPSGLLtPPQSGKK | phosphorylation down-regulates | 19561641 | SIGNOR-186418 |
| CDK2 | CDKN1B | Thr187 | NAGSVEQtPKKPGLR | phosphorylation down-regulates | 17409098 | SIGNOR-154188 |
| CDK2 | FOXK2 | Ser373 | SSRSAPAsPNHAGVL | phosphorylation up-regulates | 20810654 | SIGNOR-167830 |
| CDK2 | PRKAR1A | Ser83 | DSREDEIsPPPPNPV | phosphorylation up-regulates | 16582606 | SIGNOR-145577 |
| CDK2 | CCNE1 | Ser387 | LSEQNRAsPLPSGLL | phosphorylation down-regulates | 19561641 | SIGNOR-186414 |
| CDK2 | UBE2A | Ser120 | LDEPNPNsPANSQAA | phosphorylation up-regulates | 11953320 | SIGNOR-116508 |
| CDK2 | ESR1 | Ser294 | RAANLWPsPLMIKRS | phosphorylation up-regulates | 23390529 | SIGNOR-200867 |
| CDK2 | SMAD3 | Thr179 | PQSNIPEtPPPGYLS | phosphorylation down-regulates activity | 19114991 | SIGNOR-182971 |
| CDK2 | PGR | Ser25 | PPSPEVGsPLLCRPA | phosphorylation unknown | 11110801 | SIGNOR-84988 |
| CDK2 | RUNX1 | Ser266 | QYLGSIAsPSVHPAT | phosphorylation up-regulates activity | 16046550 | SIGNOR-138932 |
| CDK2 | RBBP8 | Thr847 | FRYIPPNtPENFWEV | phosphorylation up-regulates | 19202191 | SIGNOR-183840 |
| CDK2 | DLG1 | Ser158 | FVSHSHIsPIKPTEA | phosphorylation up-regulates | 19066288 | SIGNOR-182761 |
| CDK2 | PGR | Ser676 | LSQRFTFsPGQDIQL | phosphorylation unknown | 11110801 | SIGNOR-84996 |
| CDK2 | CDC6 | Ser74 | TPHLPPCsPPKQGKK | phosphorylation down-regulates activity | 9889196 | SIGNOR-63895 |
| CDK2 | ATRIP | Ser239 | VIKPEACsPQFGKTS | phosphorylation unknown | 17638878 | SIGNOR-156932 |
| CDK2 | RBL2 | Ser1112 | LLEDGSEsPAKRICP | phosphorylation down-regulates | 11157749 | SIGNOR-104656 |
| CDK2 | ORC2 | Thr226 | SAPVGKEtPSKRMKR | phosphorylation up-regulates | 22334659 | SIGNOR-196048 |
| CDK2 | MCM4 | Ser32 | RSEDARSsPSQRRRG | phosphorylation down-regulates activity | 12714602 | SIGNOR-100881 |
| CDK2 | USP37 | Ser628 | MVNSCITsPSTPSKK | phosphorylation up-regulates activity | 21596315 | SIGNOR-265045 |
| CDK2 | ELK4 | Ser387 | LSPVAPLsPARLQGA | phosphorylation up-regulates activity | 26028036 | SIGNOR-278210 |
| CDK2 | RNF4 | Thr26 | RTREATStPEISLEA | phosphorylation up-regulates activity | 25948581 | SIGNOR-276900 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | BRCA1 PSer1497 | phosphorylation up-regulates → | BRCA1 | 10550055 | SIGNOR-72091 |
| CDK2 | phosphorylation up-regulates → | NPM1 PThr234 | phosphorylation down-regulates ⊣ | NPM1 | 11278991 | SIGNOR-235725 |
| CDK2 | phosphorylation up-regulates → | RUNX1 PSer276 | phosphorylation down-regulates ⊣ | RUNX1 | 17015473 | SIGNOR-149976 |
| CDK2 | phosphorylation up-regulates → | SF3B1 PThr244 | phosphorylation up-regulates → | SF3B1 | 12105215 | SIGNOR-90434 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer639 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104679 |
| CDK2 | phosphorylation up-regulates → | CDK7 PThr170 | phosphorylation up-regulates → | CDK7 | 11113184 | SIGNOR-85013 |
| CDK2 | phosphorylation up-regulates → | RAD54L PSer49 | phosphorylation down-regulates ⊣ | RAD54L | 29295984 | SIGNOR-273599 |
| CDK2 | phosphorylation up-regulates → | SF3B1 PThr248 | phosphorylation up-regulates → | SF3B1 | 12105215 | SIGNOR-90438 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr487 | phosphorylation up-regulates → | MYBL2 | 9840932 | SIGNOR-62361 |
| CDK2 | phosphorylation up-regulates → | NBN PSer432 | phosphorylation up-regulates → | NBN | 22927831 | SIGNOR-279500 |
| CDK2 | phosphorylation up-regulates → | APP PThr743 | phosphorylation down-regulates ⊣ | APP | 30881282 | SIGNOR-280210 |
| CDK2 | phosphorylation up-regulates → | TTK PThr468 | phosphorylation up-regulates → | TTK | 20861309 | SIGNOR-279398 |
| CDK2 | phosphorylation up-regulates → | PTPN2 PSer304 | phosphorylation down-regulates ⊣ | PTPN2 | 15030318 | SIGNOR-123471 |
| CDK2 | phosphorylation up-regulates → | CDC6 PSer106 | phosphorylation up-regulates → | CDC6 | 10339564 | SIGNOR-67540 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer413 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104675 |
| CDK2 | phosphorylation up-regulates → | CCNA2 PSer154 | phosphorylation up-regulates → | CCNA2 | 10652300 | SIGNOR-74466 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer400 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265956 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr266 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250736 |
| CDK2 | phosphorylation up-regulates → | MCM3 PThr722 | phosphorylation up-regulates → | MCM3 | 21965652 | SIGNOR-176656 |
| CDK2 | phosphorylation up-regulates → | CDC6 PSer74 | phosphorylation down-regulates ⊣ | CDC6 | 10339564 | SIGNOR-67548 |
| CDK2 | phosphorylation up-regulates → | BCL2L1 PSer73 | phosphorylation up-regulates → | BCL2L1 | 27239332 | SIGNOR-278242 |
| CDK2 | phosphorylation up-regulates → | MCM4 PThr19 | phosphorylation down-regulates ⊣ | MCM4 | 12714602 | SIGNOR-100893 |
| CDK2 | phosphorylation up-regulates → | UBTF PSer389 | phosphorylation up-regulates → | UBTF | 11698641 | SIGNOR-235419 |
| CDK2 | phosphorylation up-regulates → | TK1 PSer13 | phosphorylation down-regulates ⊣ | TK1 | 14697231 | SIGNOR-120372 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer1112 | phosphorylation down-regulates ⊣ | RBL2 | 12006580 | SIGNOR-87492 |
| CDK2 | phosphorylation up-regulates → | NR3C1 PSer211 | phosphorylation up-regulates → | NR3C1 | 9199329 | SIGNOR-249427 |
| CDK2 | phosphorylation up-regulates → | NFYA PSer326 | phosphorylation up-regulates → | NFYA | 12857729 | SIGNOR-250743 |
| CDK2 | phosphorylation up-regulates → | RBL2 PThr417 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104699 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PSer204 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-250749 |
| CDK2 | phosphorylation up-regulates → | PLK1 PThr210 | phosphorylation up-regulates → | PLK1 | 33402344 | SIGNOR-280212 |
| CDK2 | phosphorylation up-regulates → | ING5 PThr152 | phosphorylation up-regulates → | ING5 | 25860957 | SIGNOR-279447 |
| CDK2 | phosphorylation up-regulates → | LIG1 PSer91 | phosphorylation up-regulates → | LIG1 | 12851383 | SIGNOR-103254 |
| CDK2 | phosphorylation up-regulates → | CROCC PSer1460 | phosphorylation down-regulates ⊣ | CROCC | 22610972 | SIGNOR-197593 |
| CDK2 | phosphorylation up-regulates → | CDKN1A PSer130 | phosphorylation down-regulates ⊣ | CDKN1A | 15964852 | SIGNOR-149416 |
| CDK2 | phosphorylation up-regulates → | GRK2 PSer670 | phosphorylation down-regulates ⊣ | GRK2 | 20080565 | SIGNOR-163279 |
| CDK2 | phosphorylation up-regulates → | TP63 PThr491 | phosphorylation down-regulates ⊣ | TP63 | 18769144 | SIGNOR-180767 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer952 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104691 |
| CDK2 | phosphorylation up-regulates → | CCP110 PThr566 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265959 |
| CDK2 | phosphorylation up-regulates → | MCM2 PSer13 | phosphorylation up-regulates → | MCM2 | 16446360 | SIGNOR-144000 |
| CDK2 | phosphorylation up-regulates → | NPM1 PThr234 | phosphorylation down-regulates ⊣ | NPM1 | 12058066 | SIGNOR-89609 |
| CDK2 | phosphorylation up-regulates → | SP1 PSer59 | phosphorylation up-regulates → | SP1 | 11598016 | SIGNOR-248232 |
| CDK2 | phosphorylation up-regulates → | FOXK2 PSer428 | phosphorylation up-regulates → | FOXK2 | 20810654 | SIGNOR-167834 |
| CDK2 | phosphorylation up-regulates → | MYOD1 PSer200 | phosphorylation down-regulates ⊣ | MYOD1 | 21902831 | SIGNOR-176509 |
| CDK2 | phosphorylation up-regulates → | CDK7 PSer164 | phosphorylation down-regulates ⊣ | CDK7 | 11113184 | SIGNOR-84832 |
| CDK2 | phosphorylation up-regulates → | ARID4A PSer864 | phosphorylation down-regulates ⊣ | ARID4A | 21148318 | SIGNOR-170455 |
| CDK2 | phosphorylation up-regulates → | RBL2 PThr694 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104707 |
| CDK2 | phosphorylation up-regulates → | ESR1 PSer106 | phosphorylation up-regulates → | ESR1 | 10428798 | SIGNOR-69714 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr515 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250739 |
| CDK2 | phosphorylation up-regulates → | SKP2 PSer64 | phosphorylation up-regulates → | SKP2 | 18239684 | SIGNOR-249173 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PThr8 | phosphorylation down-regulates ⊣ | SMAD3 | 19114991 | SIGNOR-182975 |
| CDK2 | phosphorylation up-regulates → | PTPN12 PSer19 | phosphorylation down-regulates ⊣ | PTPN12 | 28842430 | SIGNOR-277366 |
| CDK2 | phosphorylation up-regulates → | ATRIP PSer224 | phosphorylation up-regulates → | ATRIP | 17638878 | SIGNOR-156928 |
| CDK2 | phosphorylation up-regulates → | RBL2 PThr1097 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104695 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer170 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265958 |
| CDK2 | phosphorylation up-regulates → | CDKN2D PThr141 | phosphorylation up-regulates → | CDKN2D | 22558186 | SIGNOR-197274 |
| CDK2 | phosphorylation up-regulates → | CCDC6 PSer244 | phosphorylation up-regulates → | CCDC6 | 14712216 | SIGNOR-121198 |
| CDK2 | phosphorylation up-regulates → | ID3 PSer5 | phosphorylation down-regulates ⊣ | ID3 | 9372912 | SIGNOR-53306 |
| CDK2 | phosphorylation up-regulates → | POLL PThr553 | phosphorylation up-regulates → | POLL | 18688254 | SIGNOR-276169 |
| CDK2 | phosphorylation up-regulates → | MYC PSer62 | phosphorylation up-regulates → | MYC | 35039060 | SIGNOR-279808 |
| CDK2 | phosphorylation up-regulates → | CDH1 PThr40 | phosphorylation down-regulates ⊣ | CDH1 | 23972993 | SIGNOR-274050 |
| CDK2 | phosphorylation up-regulates → | PPP1CA PThr320 | phosphorylation down-regulates ⊣ | PPP1CA | 12202491 | SIGNOR-92265 |
| CDK2 | phosphorylation up-regulates → | CCP110 PThr194 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265961 |
| CDK2 | phosphorylation up-regulates → | RECQL4 PSer251 | phosphorylation up-regulates → | RECQL4 | 29229926 | SIGNOR-277374 |
| CDK2 | phosphorylation up-regulates → | SF3B1 PThr313 | phosphorylation down-regulates ⊣ | SF3B1 | 12105215 | SIGNOR-90442 |
| CDK2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 22369944 | SIGNOR-196372 |
| CDK2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 17601773 | SIGNOR-156509 |
| CDK2 | phosphorylation up-regulates → | FOXO1 PSer249 | phosphorylation down-regulates ⊣ | FOXO1 | 17038621 | SIGNOR-150028 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr518 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250740 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr440 | phosphorylation down-regulates ⊣ | MYBL2 | 10095772 | SIGNOR-250738 |
| CDK2 | phosphorylation up-regulates → | SOX2 PSer37 | phosphorylation up-regulates → | SOX2 | 26139602 | SIGNOR-279448 |
| CDK2 | phosphorylation up-regulates → | SOX2 PSer251 | phosphorylation up-regulates → | SOX2 | 26139602 | SIGNOR-279449 |
| CDK2 | phosphorylation up-regulates → | TOB2 PSer254 | phosphorylation up-regulates → | TOB2 | 32404348 | SIGNOR-273601 |
| CDK2 | phosphorylation up-regulates → | BRCA1 PSer1497 | phosphorylation up-regulates → | BRCA1 | 19683496 | SIGNOR-187607 |
| CDK2 | phosphorylation up-regulates → | NPAT PThr1270 | phosphorylation up-regulates → | NPAT | 10995387 | SIGNOR-82137 |
| CDK2 | phosphorylation up-regulates → | ARID4A PSer1007 | phosphorylation down-regulates ⊣ | ARID4A | 21148318 | SIGNOR-170451 |
| CDK2 | phosphorylation up-regulates → | NR3C1 PSer203 | phosphorylation up-regulates → | NR3C1 | 9199329 | SIGNOR-249426 |
| CDK2 | phosphorylation up-regulates → | ZBTB16 PThr282 | phosphorylation down-regulates ⊣ | ZBTB16 | 18246121 | SIGNOR-160630 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer516 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265963 |
| CDK2 | phosphorylation up-regulates → | CDH1 PSer36 | phosphorylation down-regulates ⊣ | CDH1 | 23972993 | SIGNOR-274049 |
| CDK2 | phosphorylation up-regulates → | ELK4 PThr194 | phosphorylation up-regulates → | ELK4 | 26028036 | SIGNOR-278211 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PSer393 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250734 |
| CDK2 | phosphorylation up-regulates → | WEE1 PSer123 | phosphorylation down-regulates ⊣ | WEE1 | 16085715 | SIGNOR-139469 |
| CDK2 | phosphorylation up-regulates → | LIG1 PSer76 | phosphorylation up-regulates → | LIG1 | 12851383 | SIGNOR-103250 |
| CDK2 | phosphorylation up-regulates → | MCM4 PSer54 | phosphorylation down-regulates ⊣ | MCM4 | 12714602 | SIGNOR-100885 |
| CDK2 | phosphorylation up-regulates → | MECOM PSer624 | phosphorylation up-regulates → | MECOM | 33082307 | SIGNOR-273426 |
| CDK2 | phosphorylation up-regulates → | RUNX1 PSer276 | phosphorylation up-regulates → | RUNX1 | 16046550 | SIGNOR-138936 |
| CDK2 | phosphorylation up-regulates → | NPAT PThr1350 | phosphorylation up-regulates → | NPAT | 10995387 | SIGNOR-82141 |
| CDK2 | phosphorylation up-regulates → | CDC6 PSer54 | phosphorylation down-regulates ⊣ | CDC6 | 10339564 | SIGNOR-67544 |
| CDK2 | phosphorylation up-regulates → | PRDX1 PThr90 | phosphorylation down-regulates ⊣ | PRDX1 | 11986303 | SIGNOR-87101 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer688 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104687 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer45 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265957 |
| CDK2 | phosphorylation up-regulates → | DLG1 PSer443 | phosphorylation up-regulates → | DLG1 | 19066288 | SIGNOR-182765 |
| CDK2 | phosphorylation up-regulates → | ZC3HC1 PSer395 | phosphorylation down-regulates ⊣ | ZC3HC1 | 17389604 | SIGNOR-154051 |
| CDK2 | phosphorylation up-regulates → | TFCP2 PSer309 | phosphorylation down-regulates ⊣ | TFCP2 | 19237534 | SIGNOR-184160 |
| CDK2 | phosphorylation up-regulates → | NFYA PSer320 | phosphorylation up-regulates → | NFYA | 12857729 | SIGNOR-250742 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer372 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265962 |
| CDK2 | phosphorylation up-regulates → | RAD9A PSer328 | phosphorylation down-regulates ⊣ | RAD9A | 23028682 | SIGNOR-199020 |
| CDK2 | phosphorylation up-regulates → | ORC2 PThr116 | phosphorylation up-regulates → | ORC2 | 11931757 | SIGNOR-116364 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer1068 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104667 |
| CDK2 | phosphorylation up-regulates → | FZR1 PSer163 | phosphorylation down-regulates ⊣ | FZR1 | 12560341 | SIGNOR-250733 |
| CDK2 | phosphorylation up-regulates → | ORC2 PThr226 | phosphorylation up-regulates → | ORC2 | 11931757 | SIGNOR-116476 |
| CDK2 | phosphorylation up-regulates → | EZH2 PThr416 | phosphorylation up-regulates → | EZH2 | 23241245 | SIGNOR-255656 |
| CDK2 | phosphorylation up-regulates → | FOXO PSer249 | phosphorylation down-regulates ⊣ | FOXO | 17038621 | SIGNOR-252892 |
| CDK2 | phosphorylation up-regulates → | SIRT1 PSer47 | phosphorylation up-regulates → | SIRT1 | 27991597 | SIGNOR-279513 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr494 | phosphorylation up-regulates → | MYBL2 | 9840932 | SIGNOR-62365 |
| CDK2 | phosphorylation up-regulates → | FZR1 PSer151 | phosphorylation down-regulates ⊣ | FZR1 | 12560341 | SIGNOR-250732 |
| CDK2 | phosphorylation up-regulates → | TK1 PSer13 | phosphorylation down-regulates ⊣ | TK1 | 12435275 | SIGNOR-95578 |
| CDK2 | phosphorylation up-regulates → | COIL PSer184 | phosphorylation up-regulates → | COIL | 11102515 | SIGNOR-84949 |
| CDK2 | phosphorylation up-regulates → | CDX2 PSer295 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250730 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer662 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104683 |
| CDK2 | phosphorylation up-regulates → | CDKN2D PSer76 | phosphorylation up-regulates → | CDKN2D | 22558186 | SIGNOR-197270 |
| CDK2 | phosphorylation up-regulates → | ID2 PSer5 | phosphorylation down-regulates ⊣ | ID2 | 9029153 | SIGNOR-46397 |
| CDK2 | phosphorylation up-regulates → | TP53 PSer315 | phosphorylation up-regulates → | TP53 | 24173284 | SIGNOR-119379 |
| CDK2 | phosphorylation up-regulates → | CDX2 PSer291 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250729 |
| CDK2 | phosphorylation up-regulates → | PGR PThr430 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-85000 |
| CDK2 | phosphorylation up-regulates → | PGR PSer20 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84980 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PSer213 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-126732 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PThr179 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-126736 |
| CDK2 | phosphorylation up-regulates → | FOXM1 PThr611 | phosphorylation up-regulates → | FOXM1 | 15024056 | SIGNOR-250731 |
| CDK2 | phosphorylation up-regulates → | HMGA1 PSer36 | phosphorylation down-regulates ⊣ | HMGA1 | 17960875 | SIGNOR-158612 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PThr8 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-217734 |
| CDK2 | phosphorylation up-regulates → | CDX2 PSer287 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-250728 |
| CDK2 | phosphorylation up-regulates → | MAP3K11 PSer770 | phosphorylation up-regulates → | MAP3K11 | 35843311 | SIGNOR-277604 |
| CDK2 | phosphorylation up-regulates → | DNMT1 PSer154 | phosphorylation up-regulates → | DNMT1 | 21565170 | SIGNOR-173681 |
| CDK2 | phosphorylation up-regulates → | PGR PSer213 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84984 |
| CDK2 | phosphorylation up-regulates → | ESR1 PSer104 | phosphorylation up-regulates → | ESR1 | 10428798 | SIGNOR-69710 |
| CDK2 | phosphorylation up-regulates → | CHEK1 PSer301 | phosphorylation up-regulates → | CHEK1 | 21765472 | SIGNOR-175083 |
| CDK2 | phosphorylation up-regulates → | TPX2 PThr72 | phosphorylation down-regulates ⊣ | TPX2 | 25688093 | SIGNOR-265099 |
| CDK2 | phosphorylation up-regulates → | RUNX1 PSer249 | phosphorylation up-regulates → | RUNX1 | 16046550 | SIGNOR-138928 |
| CDK2 | phosphorylation up-regulates → | CDK2 PThr160 | phosphorylation up-regulates → | CDK2 | 17361108 | SIGNOR-153636 |
| CDK2 | phosphorylation up-regulates → | KLF10 PSer206 | phosphorylation up-regulates → | KLF10 | 25728284 | SIGNOR-278394 |
| CDK2 | phosphorylation up-regulates → | CDC25C PSer214 | phosphorylation up-regulates → | CDC25C | 20530684 | SIGNOR-165872 |
| CDK2 | phosphorylation up-regulates → | HIRA PThr555 | phosphorylation up-regulates → | HIRA | 11238922 | SIGNOR-105548 |
| CDK2 | phosphorylation up-regulates → | RBL2 PThr642 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104703 |
| CDK2 | phosphorylation up-regulates → | PTHLH PThr121 | phosphorylation down-regulates ⊣ | PTHLH | 10373465 | SIGNOR-68548 |
| CDK2 | phosphorylation up-regulates → | NPM1 PSer70 | phosphorylation down-regulates ⊣ | NPM1 | 19933706 | SIGNOR-161805 |
| CDK2 | phosphorylation up-regulates → | RUNX1 PThr273 | phosphorylation up-regulates → | RUNX1 | 16046550 | SIGNOR-138940 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer366 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265960 |
| CDK2 | phosphorylation up-regulates → | ESR1 PSer118 | phosphorylation up-regulates → | ESR1 | 10428798 | SIGNOR-69718 |
| CDK2 | phosphorylation up-regulates → | PELP1 PSer991 | phosphorylation up-regulates → | PELP1 | 20807815 | SIGNOR-167766 |
| CDK2 | phosphorylation up-regulates → | MCM4 PThr110 | phosphorylation down-regulates ⊣ | MCM4 | 12714602 | SIGNOR-100889 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer1080 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104671 |
| CDK2 | phosphorylation up-regulates → | SIRT2 PSer368 | phosphorylation down-regulates ⊣ | SIRT2 | 18332217 | SIGNOR-177972 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PSer577 | phosphorylation up-regulates → | MYBL2 | 9840932 | SIGNOR-62353 |
| CDK2 | phosphorylation up-regulates → | TP63 PSer560 | phosphorylation down-regulates ⊣ | TP63 | 18769144 | SIGNOR-180763 |
| CDK2 | phosphorylation up-regulates → | TP73 PThr86 | phosphorylation down-regulates ⊣ | TP73 | 12676926 | SIGNOR-99746 |
| CDK2 | phosphorylation up-regulates → | TP63 PSer477 | phosphorylation down-regulates ⊣ | TP63 | 18769144 | SIGNOR-180759 |
| CDK2 | phosphorylation up-regulates → | RRN3 PSer44 | phosphorylation up-regulates → | RRN3 | 15004009 | SIGNOR-123231 |
| CDK2 | phosphorylation up-regulates → | CHEK1 PSer286 | phosphorylation up-regulates → | CHEK1 | 21765472 | SIGNOR-175079 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr405 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250737 |
| CDK2 | phosphorylation up-regulates → | LIG3 PSer210 | phosphorylation down-regulates ⊣ | LIG3 | 17040896 | SIGNOR-150121 |
| CDK2 | phosphorylation up-regulates → | SMAD2 PThr8 | phosphorylation down-regulates ⊣ | SMAD2 | 19201832 | SIGNOR-279678 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr520 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250741 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PSer213 | phosphorylation down-regulates ⊣ | SMAD3 | 19114991 | SIGNOR-182967 |
| CDK2 | phosphorylation up-regulates → | CCNE1 PSer399 | phosphorylation down-regulates ⊣ | CCNE1 | 14536078 | SIGNOR-118555 |
| CDK2 | phosphorylation up-regulates → | RNF138 PThr27 | phosphorylation up-regulates → | RNF138 | 38309501 | SIGNOR-277831 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PThr8 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-126740 |
| CDK2 | phosphorylation up-regulates → | LIG1 PSer51 | phosphorylation up-regulates → | LIG1 | 12851383 | SIGNOR-103246 |
| CDK2 | phosphorylation up-regulates → | CDX2 PSer283 | phosphorylation down-regulates ⊣ | CDX2 | 16027724 | SIGNOR-138825 |
| CDK2 | phosphorylation up-regulates → | NR1I2 PSer350 | phosphorylation down-regulates ⊣ | NR1I2 | 35053380 | SIGNOR-279397 |
| CDK2 | phosphorylation up-regulates → | RPL12 PSer38 | phosphorylation down-regulates ⊣ | RPL12 | 18847512 | SIGNOR-181603 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PSer213 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-232134 |
| CDK2 | phosphorylation up-regulates → | MCM3AP PSer508 | phosphorylation up-regulates → | MCM3AP | 11526238 | SIGNOR-262734 |
| CDK2 | phosphorylation up-regulates → | RNF4 PThr112 | phosphorylation up-regulates → | RNF4 | 25948581 | SIGNOR-276901 |
| CDK2 | phosphorylation up-regulates → | UHRF1 PSer675 | phosphorylation down-regulates ⊣ | UHRF1 | 26727879 | SIGNOR-277192 |
| CDK2 | phosphorylation up-regulates → | ZBTB16 PSer197 | phosphorylation down-regulates ⊣ | ZBTB16 | 18246121 | SIGNOR-160626 |
| CDK2 | phosphorylation up-regulates → | CCNO PSer81 | phosphorylation up-regulates → | CCNO | 25364462 | SIGNOR-275615 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PSer452 | phosphorylation up-regulates → | MYBL2 | 10593981 | SIGNOR-250735 |
| CDK2 | phosphorylation up-regulates → | GATA3 PThr156 | phosphorylation down-regulates ⊣ | GATA3 | 24820417 | SIGNOR-276634 |
| CDK2 | phosphorylation up-regulates → | PGR PSer294 | phosphorylation down-regulates ⊣ | PGR | 10655479 | SIGNOR-74708 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer1044 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104660 |
| CDK2 | phosphorylation up-regulates → | MYBL2 PThr444 | phosphorylation up-regulates → | MYBL2 | 9840932 | SIGNOR-62357 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PSer208 | phosphorylation down-regulates ⊣ | SMAD3 | 15241418 | SIGNOR-250750 |
| CDK2 | phosphorylation up-regulates → | PGR PSer554 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84992 |
| CDK2 | phosphorylation up-regulates → | RB1 PThr821 | phosphorylation down-regulates ⊣ | RB1 | 9139732 | SIGNOR-47895 |
| CDK2 | phosphorylation up-regulates → | CDC6 PSer54 | phosphorylation down-regulates ⊣ | CDC6 | 9889196 | SIGNOR-63891 |
| CDK2 | phosphorylation up-regulates → | CDC25A PSer263 | phosphorylation down-regulates ⊣ | CDC25A | 17110335 | SIGNOR-150839 |
| CDK2 | phosphorylation up-regulates → | CCNE1 PThr395 | phosphorylation down-regulates ⊣ | CCNE1 | 19561641 | SIGNOR-186418 |
| CDK2 | phosphorylation up-regulates → | CDKN1B PThr187 | phosphorylation down-regulates ⊣ | CDKN1B | 17409098 | SIGNOR-154188 |
| CDK2 | phosphorylation up-regulates → | FOXK2 PSer373 | phosphorylation up-regulates → | FOXK2 | 20810654 | SIGNOR-167830 |
| CDK2 | phosphorylation up-regulates → | PRKAR1A PSer83 | phosphorylation up-regulates → | PRKAR1A | 16582606 | SIGNOR-145577 |
| CDK2 | phosphorylation up-regulates → | CCNE1 PSer387 | phosphorylation down-regulates ⊣ | CCNE1 | 19561641 | SIGNOR-186414 |
| CDK2 | phosphorylation up-regulates → | UBE2A PSer120 | phosphorylation up-regulates → | UBE2A | 11953320 | SIGNOR-116508 |
| CDK2 | phosphorylation up-regulates → | ESR1 PSer294 | phosphorylation up-regulates → | ESR1 | 23390529 | SIGNOR-200867 |
| CDK2 | phosphorylation up-regulates → | SMAD3 PThr179 | phosphorylation down-regulates ⊣ | SMAD3 | 19114991 | SIGNOR-182971 |
| CDK2 | phosphorylation up-regulates → | PGR PSer25 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84988 |
| CDK2 | phosphorylation up-regulates → | RUNX1 PSer266 | phosphorylation up-regulates → | RUNX1 | 16046550 | SIGNOR-138932 |
| CDK2 | phosphorylation up-regulates → | RBBP8 PThr847 | phosphorylation up-regulates → | RBBP8 | 19202191 | SIGNOR-183840 |
| CDK2 | phosphorylation up-regulates → | DLG1 PSer158 | phosphorylation up-regulates → | DLG1 | 19066288 | SIGNOR-182761 |
| CDK2 | phosphorylation up-regulates → | PGR PSer676 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84996 |
| CDK2 | phosphorylation up-regulates → | CDC6 PSer74 | phosphorylation down-regulates ⊣ | CDC6 | 9889196 | SIGNOR-63895 |
| CDK2 | phosphorylation up-regulates → | ATRIP PSer239 | phosphorylation down-regulates ⊣ | ATRIP | 17638878 | SIGNOR-156932 |
| CDK2 | phosphorylation up-regulates → | RBL2 PSer1112 | phosphorylation down-regulates ⊣ | RBL2 | 11157749 | SIGNOR-104656 |
| CDK2 | phosphorylation up-regulates → | ORC2 PThr226 | phosphorylation up-regulates → | ORC2 | 22334659 | SIGNOR-196048 |
| CDK2 | phosphorylation up-regulates → | MCM4 PSer32 | phosphorylation down-regulates ⊣ | MCM4 | 12714602 | SIGNOR-100881 |
| CDK2 | phosphorylation up-regulates → | USP37 PSer628 | phosphorylation up-regulates → | USP37 | 21596315 | SIGNOR-265045 |
| CDK2 | phosphorylation up-regulates → | ELK4 PSer387 | phosphorylation up-regulates → | ELK4 | 26028036 | SIGNOR-278210 |
| CDK2 | phosphorylation up-regulates → | RNF4 PThr26 | phosphorylation up-regulates → | RNF4 | 25948581 | SIGNOR-276900 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation down-regulates | FOXO | SIGNOR-252891 |
| CDK2 | phosphorylation → up-regulates | BRCA1 | SIGNOR-72091 |
| CDK2 | phosphorylation → down-regulates activity | NPM1 | SIGNOR-235725 |
| CDK2 | phosphorylation → down-regulates activity | RUNX1 | SIGNOR-149976 |
| CDK2 | phosphorylation → up-regulates | SF3B1 | SIGNOR-90434 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104679 |
| CDK2 | phosphorylation → up-regulates | CDK7 | SIGNOR-85013 |
| CDK2 | phosphorylation → down-regulates activity | RAD54L | SIGNOR-273599 |
| CDK2 | phosphorylation → up-regulates | SF3B1 | SIGNOR-90438 |
| CDK2 | phosphorylation → up-regulates | MYBL2 | SIGNOR-62361 |
| CDK2 | phosphorylation → up-regulates activity | NBN | SIGNOR-279500 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | APP | SIGNOR-280210 |
| CDK2 | phosphorylation → down-regulates activity | BARD1 | SIGNOR-280211 |
| CDK2 | phosphorylation → up-regulates quantity by stabilization | TTK | SIGNOR-279398 |
| CDK2 | phosphorylation → unknown | PTPN2 | SIGNOR-123471 |
| CDK2 | phosphorylation → up-regulates | CDC6 | SIGNOR-67540 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104675 |
| CDK2 | phosphorylation → up-regulates | CCNA2 | SIGNOR-74466 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265956 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250736 |
| CDK2 | phosphorylation → up-regulates | MCM3 | SIGNOR-176656 |
| CDK2 | phosphorylation → down-regulates activity | CDC6 | SIGNOR-67548 |
| CDK2 | phosphorylation → up-regulates activity | BCL2L1 | SIGNOR-278242 |
| CDK2 | phosphorylation → down-regulates activity | MCM4 | SIGNOR-100893 |
| CDK2 | phosphorylation → up-regulates activity | UBTF | SIGNOR-235419 |
| CDK2 | phosphorylation → down-regulates activity | CDH1 | SIGNOR-279512 |
| CDK2 | phosphorylation down-regulates | TK1 | SIGNOR-120372 |
| CDK2 | phosphorylation down-regulates | RBL2 | SIGNOR-87492 |
| CDK2 | phosphorylation → up-regulates activity | NR3C1 | SIGNOR-249427 |
| CDK2 | phosphorylation → up-regulates activity | NFYA | SIGNOR-250743 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104699 |
| CDK2 | phosphorylation → unknown | SMAD3 | SIGNOR-250749 |
| CDK2 | phosphorylation → up-regulates activity | PLK1 | SIGNOR-280212 |
| CDK2 | phosphorylation → down-regulates activity | NCOR2 | SIGNOR-278306 |
| CDK2 | phosphorylation → up-regulates quantity | ING5 | SIGNOR-279447 |
| CDK2 | phosphorylation → up-regulates activity | LIG1 | SIGNOR-103254 |
| CDK2 | phosphorylation down-regulates | CROCC | SIGNOR-197593 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDKN1A | SIGNOR-149416 |
| CDK2 | phosphorylation down-regulates | GRK2 | SIGNOR-163279 |
| CDK2 | phosphorylation down-regulates | TP63 | SIGNOR-180767 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104691 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265959 |
| CDK2 | phosphorylation → up-regulates | MCM2 | SIGNOR-144000 |
| CDK2 | phosphorylation → down-regulates activity | NPM1 | SIGNOR-89609 |
| CDK2 | phosphorylation → up-regulates activity | SP1 | SIGNOR-248232 |
| CDK2 | phosphorylation → up-regulates | FOXK2 | SIGNOR-167834 |
| CDK2 | phosphorylation down-regulates | MYOD1 | SIGNOR-176509 |
| CDK2 | phosphorylation → unknown | CDK7 | SIGNOR-84832 |
| CDK2 | phosphorylation → up-regulates activity | PARP1 | SIGNOR-279146 |
| CDK2 | phosphorylation down-regulates | ARID4A | SIGNOR-170455 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104707 |
| CDK2 | phosphorylation down-regulates | RB1 | SIGNOR-176512 |
| CDK2 | phosphorylation → up-regulates | ESR1 | SIGNOR-69714 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250739 |
| CDK2 | phosphorylation → up-regulates activity | LARP1 | SIGNOR-279015 |
| CDK2 | phosphorylation → up-regulates quantity by stabilization | SKP2 | SIGNOR-249173 |
| CDK2 | phosphorylation down-regulates | SMAD3 | SIGNOR-182975 |
| CDK2 | phosphorylation → down-regulates activity | PTPN12 | SIGNOR-277366 |
| CDK2 | phosphorylation → up-regulates | ATRIP | SIGNOR-156928 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104695 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265958 |
| CDK2 | phosphorylation → up-regulates | CDKN2D | SIGNOR-197274 |
| CDK2 | phosphorylation → up-regulates | CCDC6 | SIGNOR-121198 |
| CDK2 | phosphorylation down-regulates | ID3 | SIGNOR-53306 |
| CDK2 | phosphorylation → up-regulates quantity by stabilization | POLL | SIGNOR-276169 |
| CDK2 | phosphorylation → up-regulates quantity by stabilization | MYC | SIGNOR-279808 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDH1 | SIGNOR-274050 |
| CDK2 | phosphorylation → down-regulates activity | PPP1CA | SIGNOR-92265 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265961 |
| CDK2 | phosphorylation → up-regulates activity | RECQL4 | SIGNOR-277374 |
| CDK2 | phosphorylation → unknown | SF3B1 | SIGNOR-90442 |
| CDK2 | phosphorylation → up-regulates | CEBPB | SIGNOR-196372 |
| CDK2 | phosphorylation → up-regulates | CEBPB | SIGNOR-156509 |
| CDK2 | phosphorylation down-regulates | FOXO1 | SIGNOR-150028 |
| CDK2 | phosphorylation down-regulates | FOXO4 | SIGNOR-183655 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250740 |
| CDK2 | phosphorylation → unknown | MYBL2 | SIGNOR-250738 |
| CDK2 | phosphorylation → up-regulates activity | SOX2 | SIGNOR-279448 |
| CDK2 | phosphorylation → up-regulates activity | SOX2 | SIGNOR-279449 |
| CDK2 | phosphorylation → up-regulates activity | POLL | SIGNOR-278919 |
| CDK2 | phosphorylation → up-regulates activity | TOB2 | SIGNOR-273601 |
| CDK2 | phosphorylation → up-regulates | BRCA1 | SIGNOR-187607 |
| CDK2 | phosphorylation → up-regulates | NPAT | SIGNOR-82137 |
| CDK2 | phosphorylation down-regulates | ARID4A | SIGNOR-170451 |
| CDK2 | phosphorylation → up-regulates activity | NR3C1 | SIGNOR-249426 |
| CDK2 | phosphorylation down-regulates | ZBTB16 | SIGNOR-160630 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265963 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDH1 | SIGNOR-274049 |
| CDK2 | phosphorylation → up-regulates activity | ELK4 | SIGNOR-278211 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250734 |
| CDK2 | phosphorylation down-regulates | WEE1 | SIGNOR-139469 |
| CDK2 | phosphorylation → up-regulates activity | LIG1 | SIGNOR-103250 |
| CDK2 | phosphorylation → down-regulates activity | MCM4 | SIGNOR-100885 |
| CDK2 | phosphorylation → up-regulates activity | MECOM | SIGNOR-273426 |
| CDK2 | phosphorylation → up-regulates activity | RUNX1 | SIGNOR-138936 |
| CDK2 | phosphorylation → up-regulates | NPAT | SIGNOR-82141 |
| CDK2 | phosphorylation → down-regulates activity | CDC6 | SIGNOR-67544 |
| CDK2 | phosphorylation down-regulates | PRDX1 | SIGNOR-87101 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104687 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265957 |
| CDK2 | phosphorylation → up-regulates | DLG1 | SIGNOR-182765 |
| CDK2 | phosphorylation down-regulates | ZC3HC1 | SIGNOR-154051 |
| CDK2 | phosphorylation down-regulates | TFCP2 | SIGNOR-184160 |
| CDK2 | phosphorylation → up-regulates activity | NFYA | SIGNOR-250742 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265962 |
| CDK2 | phosphorylation → unknown | RAD9A | SIGNOR-199020 |
| CDK2 | phosphorylation → up-regulates | ORC2 | SIGNOR-116364 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104667 |
| CDK2 | phosphorylation → down-regulates activity | FZR1 | SIGNOR-250733 |
| CDK2 | phosphorylation → up-regulates | ORC2 | SIGNOR-116476 |
| CDK2 | phosphorylation → up-regulates activity | EZH2 | SIGNOR-255656 |
| CDK2 | phosphorylation down-regulates | FOXO | SIGNOR-252892 |
| CDK2 | phosphorylation → up-regulates activity | SIRT1 | SIGNOR-279513 |
| CDK2 | phosphorylation → up-regulates | MYBL2 | SIGNOR-62365 |
| CDK2 | phosphorylation → down-regulates activity | CDC20 | SIGNOR-279322 |
| CDK2 | phosphorylation → down-regulates activity | FZR1 | SIGNOR-250732 |
| CDK2 | phosphorylation down-regulates | TK1 | SIGNOR-95578 |
| CDK2 | phosphorylation → up-regulates | COIL | SIGNOR-84949 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250730 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104683 |
| CDK2 | phosphorylation → down-regulates activity | PP1 | SIGNOR-264650 |
| CDK2 | phosphorylation → up-regulates | CDKN2D | SIGNOR-197270 |
| CDK2 | phosphorylation down-regulates | ID2 | SIGNOR-46397 |
| CDK2 | phosphorylation → up-regulates activity | TP53 | SIGNOR-119379 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250729 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-85000 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84980 |
| CDK2 | phosphorylation down-regulates | SMAD3 | SIGNOR-126732 |
| CDK2 | phosphorylation → down-regulates activity | SMAD3 | SIGNOR-126736 |
| CDK2 | phosphorylation → up-regulates activity | FOXM1 | SIGNOR-250731 |
| CDK2 | phosphorylation down-regulates | HMGA1 | SIGNOR-158612 |
| CDK2 | phosphorylation → down-regulates activity | SMAD3 | SIGNOR-217734 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-250728 |
| CDK2 | phosphorylation → up-regulates activity | MAP3K11 | SIGNOR-277604 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | PTPN6 | SIGNOR-279147 |
| CDK2 | phosphorylation → up-regulates | DNMT1 | SIGNOR-173681 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84984 |
| CDK2 | phosphorylation → up-regulates | ESR1 | SIGNOR-69710 |
| CDK2 | phosphorylation → up-regulates | CHEK1 | SIGNOR-175083 |
| CDK2 | phosphorylation → down-regulates activity | TPX2 | SIGNOR-265099 |
| CDK2 | phosphorylation → up-regulates activity | RUNX1 | SIGNOR-138928 |
| CDK2 | phosphorylation → up-regulates | CDK2 | SIGNOR-153636 |
| CDK2 | phosphorylation → up-regulates quantity | KLF10 | SIGNOR-278394 |
| CDK2 | phosphorylation → up-regulates | CDC25C | SIGNOR-165872 |
| CDK2 | phosphorylation → up-regulates activity | HIRA | SIGNOR-105548 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104703 |
| CDK2 | phosphorylation down-regulates | PTHLH | SIGNOR-68548 |
| CDK2 | phosphorylation → unknown | NPM1 | SIGNOR-161805 |
| CDK2 | phosphorylation → up-regulates activity | RUNX1 | SIGNOR-138940 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265960 |
| CDK2 | phosphorylation → up-regulates | ESR1 | SIGNOR-69718 |
| CDK2 | phosphorylation → up-regulates | PELP1 | SIGNOR-167766 |
| CDK2 | phosphorylation → down-regulates activity | MCM4 | SIGNOR-100889 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104671 |
| CDK2 | phosphorylation down-regulates | SIRT2 | SIGNOR-177972 |
| CDK2 | phosphorylation → up-regulates | MYBL2 | SIGNOR-62353 |
| CDK2 | phosphorylation down-regulates | TP63 | SIGNOR-180763 |
| CDK2 | phosphorylation → down-regulates activity | TP73 | SIGNOR-99746 |
| CDK2 | phosphorylation down-regulates | TP63 | SIGNOR-180759 |
| CDK2 | phosphorylation → up-regulates | RRN3 | SIGNOR-123231 |
| CDK2 | phosphorylation → up-regulates | CHEK1 | SIGNOR-175079 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250737 |
| CDK2 | phosphorylation down-regulates | LIG3 | SIGNOR-150121 |
| CDK2 | phosphorylation → down-regulates activity | SMAD2 | SIGNOR-279678 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250741 |
| CDK2 | phosphorylation down-regulates | SMAD3 | SIGNOR-182967 |
| CDK2 | phosphorylation down-regulates | CCNE1 | SIGNOR-118555 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | RAD51 | SIGNOR-280213 |
| CDK2 | phosphorylation → up-regulates activity | RNF138 | SIGNOR-277831 |
| CDK2 | phosphorylation down-regulates | SMAD3 | SIGNOR-126740 |
| CDK2 | phosphorylation → up-regulates activity | LIG1 | SIGNOR-103246 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | CDX2 | SIGNOR-138825 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | NR1I2 | SIGNOR-279397 |
| CDK2 | phosphorylation → unknown | RPL12 | SIGNOR-181603 |
| CDK2 | phosphorylation → down-regulates activity | SMAD3 | SIGNOR-232134 |
| CDK2 | phosphorylation → up-regulates activity | MCM3AP | SIGNOR-262734 |
| CDK2 | phosphorylation → up-regulates activity | RNF4 | SIGNOR-276901 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | UHRF1 | SIGNOR-277192 |
| CDK2 | phosphorylation down-regulates | ZBTB16 | SIGNOR-160626 |
| CDK2 | phosphorylation → up-regulates activity | CCNO | SIGNOR-275615 |
| CDK2 | phosphorylation → up-regulates activity | MYBL2 | SIGNOR-250735 |
| CDK2 | phosphorylation down-regulates quantity by destabilization | GATA3 | SIGNOR-276634 |
| CDK2 | phosphorylation → up-regulates activity | RNF157 | SIGNOR-279016 |
| CDK2 | phosphorylation down-regulates | PGR | SIGNOR-74708 |
| CDK2 | phosphorylation → unknown | RBL2 | SIGNOR-104660 |
| CDK2 | phosphorylation → up-regulates | MYBL2 | SIGNOR-62357 |
| CDK2 | phosphorylation → unknown | SMAD3 | SIGNOR-250750 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84992 |
| CDK2 | phosphorylation down-regulates | RB1 | SIGNOR-47895 |
| CDK2 | phosphorylation → down-regulates activity | CDC6 | SIGNOR-63891 |
| CDK2 | phosphorylation down-regulates | CDC25A | SIGNOR-150839 |
| CDK2 | phosphorylation down-regulates | CCNE1 | SIGNOR-186418 |
| CDK2 | phosphorylation down-regulates | CDKN1B | SIGNOR-154188 |
| CDK2 | phosphorylation → up-regulates | FOXK2 | SIGNOR-167830 |
| CDK2 | phosphorylation → up-regulates | PRKAR1A | SIGNOR-145577 |
| CDK2 | phosphorylation down-regulates | CCNE1 | SIGNOR-186414 |
| CDK2 | phosphorylation → up-regulates | UBE2A | SIGNOR-116508 |
| CDK2 | phosphorylation → up-regulates | ESR1 | SIGNOR-200867 |
| CDK2 | phosphorylation → down-regulates activity | SMAD3 | SIGNOR-182971 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84988 |
| CDK2 | phosphorylation → up-regulates activity | RUNX1 | SIGNOR-138932 |
| CDK2 | phosphorylation → up-regulates | RBBP8 | SIGNOR-183840 |
| CDK2 | phosphorylation → up-regulates | DLG1 | SIGNOR-182761 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84996 |
| CDK2 | phosphorylation → down-regulates activity | CDC6 | SIGNOR-63895 |
| CDK2 | phosphorylation → unknown | ATRIP | SIGNOR-156932 |
| CDK2 | phosphorylation down-regulates | RBL2 | SIGNOR-104656 |
| CDK2 | phosphorylation → up-regulates | ORC2 | SIGNOR-196048 |
| CDK2 | phosphorylation → down-regulates activity | MCM4 | SIGNOR-100881 |
| CDK2 | phosphorylation → up-regulates activity | USP37 | SIGNOR-265045 |
| CDK2 | phosphorylation → up-regulates activity | ELK4 | SIGNOR-278210 |
| CDK2 | phosphorylation → up-regulates activity | RNF4 | SIGNOR-276900 |