| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GRK6 | CXCR2 | – | phosphorylation down-regulates quantity | 28529637 | SIGNOR-279782 | |
| GRK2 | CXCR2 | – | phosphorylation down-regulates activity | 22634615 | SIGNOR-260647 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GRK6 | phosphorylation → down-regulates quantity | CXCR2 | SIGNOR-279782 |
| GRK2 | phosphorylation → down-regulates activity | CXCR2 | SIGNOR-260647 |