Entity Details

Name EGFR_Tyr13
ID P25098
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EGFRGRK2Tyr13AVLADVSyLMAMEKSphosphorylation
up-regulates activity		23904266SIGNOR-279368
SRCGRK2Tyr13AVLADVSyLMAMEKSphosphorylation
up-regulates activity		16725308SIGNOR-266307
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
GRK2
PTyr13		phosphorylation
up-regulates
→		GRK223904266SIGNOR-279368
SRCphosphorylation
up-regulates
→
GRK2
PTyr13		phosphorylation
up-regulates
→		GRK216725308SIGNOR-266307
Regulator Mechanism/Effect Target SIGNOR-ID
EGFRphosphorylation
→
up-regulates activity 		GRK2SIGNOR-279368
SRCphosphorylation
→
up-regulates activity 		GRK2SIGNOR-266307