| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LYN | YY1 | Tyr383 | IHTGDRPyVCPFDGC | phosphorylation down-regulates activity | 26198631 | SIGNOR-276928 |
| AURKB | YY1 | Ser180 | KKGGGKKsGKKSYLS | phosphorylation up-regulates | 23226345 | SIGNOR-200075 |
| LYN | YY1 | Tyr8 | MASGDTLyIATDGSE | phosphorylation down-regulates activity | 26198631 | SIGNOR-276930 |
| YES1 | YY1 | – | phosphorylation down-regulates activity | 26198631 | SIGNOR-276941 | |
| CSNK2A1 | YY1 | Ser118 | EVVGGDDsDGLRAED | phosphorylation up-regulates | 23226345 | SIGNOR-200083 |
| PLK1 | YY1 | Thr39 | PVETIETtVVGEEEE | phosphorylation up-regulates | 23226345 | SIGNOR-200087 |
| LYN | YY1 | Tyr254 | SPPDYSEyMTGKKLP | phosphorylation down-regulates activity | 26198631 | SIGNOR-276929 |
| SRC | YY1 | – | phosphorylation down-regulates activity | 26198631 | SIGNOR-276940 | |
| AURKB | YY1 | Ser184 | GKKSGKKsYLSGGAG | phosphorylation up-regulates | 23226345 | SIGNOR-200079 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LYN | phosphorylation up-regulates → | YY1 PTyr383 | phosphorylation down-regulates ⊣ | YY1 | 26198631 | SIGNOR-276928 |
| AURKB | phosphorylation up-regulates → | YY1 PSer180 | phosphorylation up-regulates → | YY1 | 23226345 | SIGNOR-200075 |
| LYN | phosphorylation up-regulates → | YY1 PTyr8 | phosphorylation down-regulates ⊣ | YY1 | 26198631 | SIGNOR-276930 |
| CSNK2A1 | phosphorylation up-regulates → | YY1 PSer118 | phosphorylation up-regulates → | YY1 | 23226345 | SIGNOR-200083 |
| PLK1 | phosphorylation up-regulates → | YY1 PThr39 | phosphorylation up-regulates → | YY1 | 23226345 | SIGNOR-200087 |
| LYN | phosphorylation up-regulates → | YY1 PTyr254 | phosphorylation down-regulates ⊣ | YY1 | 26198631 | SIGNOR-276929 |
| AURKB | phosphorylation up-regulates → | YY1 PSer184 | phosphorylation up-regulates → | YY1 | 23226345 | SIGNOR-200079 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LYN | phosphorylation → down-regulates activity | YY1 | SIGNOR-276928 |
| AURKB | phosphorylation → up-regulates | YY1 | SIGNOR-200075 |
| LYN | phosphorylation → down-regulates activity | YY1 | SIGNOR-276930 |
| YES1 | phosphorylation → down-regulates activity | YY1 | SIGNOR-276941 |
| CSNK2A1 | phosphorylation → up-regulates | YY1 | SIGNOR-200083 |
| PLK1 | phosphorylation → up-regulates | YY1 | SIGNOR-200087 |
| LYN | phosphorylation → down-regulates activity | YY1 | SIGNOR-276929 |
| SRC | phosphorylation → down-regulates activity | YY1 | SIGNOR-276940 |
| AURKB | phosphorylation → up-regulates | YY1 | SIGNOR-200079 |
