| Name | MST1 |
| ID | P26927 |
| Role | kinase |
| Enzymatic Domains |
PAN 21-105 PROSITE-ProRule
Kringle 1 110-186 PROSITE-ProRule
Kringle 2 191-268 PROSITE-ProRule
Kringle 3 283-361 PROSITE-ProRule
Kringle 4 370-448 PROSITE-ProRule
Peptidase S1 484-709 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MST1 | PRKCA | Ser226 | LNPQWNEsFTFKLKP | phosphorylation up-regulates activity | 26414765 | SIGNOR-277179 |
| MST1 | PRKCA | Thr228 | PQWNESFtFKLKPSD | phosphorylation up-regulates activity | 26414765 | SIGNOR-277178 |
| MST1 | H2BC3 | Ser15 | APAPKKGsKKAITKA | phosphorylation unknown | 21212262 | SIGNOR-171005 |
| MST1 | STK4 | Thr183 | DTMAKRNtVIGTPFW | phosphorylation up-regulates | 11805089 | SIGNOR-114289 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MST1 | phosphorylation up-regulates → | PRKCA PSer226 | phosphorylation up-regulates → | PRKCA | 26414765 | SIGNOR-277179 |
| MST1 | phosphorylation up-regulates → | PRKCA PThr228 | phosphorylation up-regulates → | PRKCA | 26414765 | SIGNOR-277178 |
| MST1 | phosphorylation up-regulates → | H2BC3 PSer15 | phosphorylation down-regulates ⊣ | H2BC3 | 21212262 | SIGNOR-171005 |
| MST1 | phosphorylation up-regulates → | STK4 PThr183 | phosphorylation up-regulates → | STK4 | 11805089 | SIGNOR-114289 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MST1 | phosphorylation → up-regulates activity | PRKCA | SIGNOR-277179 |
| MST1 | phosphorylation → up-regulates activity | PRKCA | SIGNOR-277178 |
| MST1 | phosphorylation → unknown | H2BC3 | SIGNOR-171005 |
| MST1 | phosphorylation → up-regulates | STK4 | SIGNOR-114289 |