Entity Details

Name MAPK1_Thr456
ID P27708
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ERK1/2CADThr456KVYFLPItPHYVTQVphosphorylation
up-regulates activity		17485345SIGNOR-267441
MAPK1CADThr456KVYFLPItPHYVTQVphosphorylation
up-regulates		15890648SIGNOR-137171
MAPK3CADThr456KVYFLPItPHYVTQVphosphorylation
up-regulates		15890648SIGNOR-137179
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ERK1/2phosphorylation
up-regulates
→
CAD
PThr456		phosphorylation
up-regulates
→		CAD17485345SIGNOR-267441
MAPK1phosphorylation
up-regulates
→
CAD
PThr456		phosphorylation
up-regulates
→		CAD15890648SIGNOR-137171
MAPK3phosphorylation
up-regulates
→
CAD
PThr456		phosphorylation
up-regulates
→		CAD15890648SIGNOR-137179
Regulator Mechanism/Effect Target SIGNOR-ID
ERK1/2phosphorylation
→
up-regulates activity 		CADSIGNOR-267441
MAPK1phosphorylation
→
up-regulates 		CADSIGNOR-137171
MAPK3phosphorylation
→
up-regulates 		CADSIGNOR-137179