Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CHEK1	MAP4	Thr521 View in OncoXplorer	MALGKDVtPPPETEV	phosphorylation down-regulates quantity by destabilization	36991467	SIGNOR-277846
MARK1	MAP4	Ser1073 View in OncoXplorer	KAQAKVGsLDNVGHL	phosphorylation down-regulates activity	8631898	SIGNOR-250169
MARK1	MAP4	Ser928 View in OncoXplorer	SRLATNTsAPDLKNV	phosphorylation down-regulates activity	8631898	SIGNOR-250170
CDK1	MAP4	Ser787 View in OncoXplorer	KAPEKRAsPSKPASA	phosphorylation down-regulates	9398320	SIGNOR-53739
CDK1	MAP4	Ser787 View in OncoXplorer	KAPEKRAsPSKPASA	phosphorylation down-regulates activity	10791892	SIGNOR-277459
MARK1	MAP4	Ser941 View in OncoXplorer	NVRSKVGsTENIKHQ	phosphorylation down-regulates activity	8631898	SIGNOR-250171
CDK1	MAP4	Ser696 View in OncoXplorer	PNKELPPsPEKKTKP	phosphorylation unknown	10791892	SIGNOR-277461
TTK	MAP4	Thr927 View in OncoXplorer	LSRLATNtSAPDLKN	phosphorylation down-regulates quantity by destabilization	31253867	SIGNOR-277462
CDK1	MAP4	Ser696 View in OncoXplorer	PNKELPPsPEKKTKP	phosphorylation down-regulates	9398320	SIGNOR-53735
CDK1	MAP4	Ser787 View in OncoXplorer	KAPEKRAsPSKPASA	phosphorylation down-regulates	10791892	SIGNOR-77087
TTK	MAP4	Ser928 View in OncoXplorer	SRLATNTsAPDLKNV	phosphorylation down-regulates quantity by destabilization	31253867	SIGNOR-277458

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CHEK1	phosphorylation up-regulates →	MAP4 PThr521	phosphorylation down-regulates ⊣	MAP4	36991467	SIGNOR-277846
MARK1	phosphorylation up-regulates →	MAP4 PSer1073	phosphorylation down-regulates ⊣	MAP4	8631898	SIGNOR-250169
MARK1	phosphorylation up-regulates →	MAP4 PSer928	phosphorylation down-regulates ⊣	MAP4	8631898	SIGNOR-250170
CDK1	phosphorylation up-regulates →	MAP4 PSer787	phosphorylation down-regulates ⊣	MAP4	9398320	SIGNOR-53739
CDK1	phosphorylation up-regulates →	MAP4 PSer787	phosphorylation down-regulates ⊣	MAP4	10791892	SIGNOR-277459
MARK1	phosphorylation up-regulates →	MAP4 PSer941	phosphorylation down-regulates ⊣	MAP4	8631898	SIGNOR-250171
CDK1	phosphorylation up-regulates →	MAP4 PSer696	phosphorylation down-regulates ⊣	MAP4	10791892	SIGNOR-277461
TTK	phosphorylation up-regulates →	MAP4 PThr927	phosphorylation down-regulates ⊣	MAP4	31253867	SIGNOR-277462
CDK1	phosphorylation up-regulates →	MAP4 PSer696	phosphorylation down-regulates ⊣	MAP4	9398320	SIGNOR-53735
CDK1	phosphorylation up-regulates →	MAP4 PSer787	phosphorylation down-regulates ⊣	MAP4	10791892	SIGNOR-77087
TTK	phosphorylation up-regulates →	MAP4 PSer928	phosphorylation down-regulates ⊣	MAP4	31253867	SIGNOR-277458

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CHEK1	phosphorylation down-regulates quantity by destabilization	MAP4	SIGNOR-277846
MARK1	phosphorylation → down-regulates activity	MAP4	SIGNOR-250169
MARK1	phosphorylation → down-regulates activity	MAP4	SIGNOR-250170
CDK1	phosphorylation down-regulates	MAP4	SIGNOR-53739
CDK1	phosphorylation → down-regulates activity	MAP4	SIGNOR-277459
MARK1	phosphorylation → down-regulates activity	MAP4	SIGNOR-250171
CDK1	phosphorylation → unknown	MAP4	SIGNOR-277461
TTK	phosphorylation down-regulates quantity by destabilization	MAP4	SIGNOR-277462
CDK1	phosphorylation down-regulates	MAP4	SIGNOR-53735
CDK1	phosphorylation down-regulates	MAP4	SIGNOR-77087
TTK	phosphorylation down-regulates quantity by destabilization	MAP4	SIGNOR-277458