| Name | PTPN4 |
| ID | P29074 |
| Role | phosphatase |
| Enzymatic Domains |
FERM 29-312 PROSITE-ProRule
PDZ 517-589 PROSITE-ProRule
Tyrosine-protein phosphatase 655-911 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN4 | STAT3 | Tyr705 | DPGSAAPyLKTKFIC | dephosphorylation down-regulates activity | 31025789 | SIGNOR-277057 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN4 | dephosphorylation down-regulates ⊣ | STAT3 PTyr705 | dephosphorylation up-regulates → | STAT3 | 31025789 | SIGNOR-277057 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN4 | dephosphorylation → down-regulates activity | STAT3 | SIGNOR-277057 |