| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ACP1 | EPHA2 | Tyr772 | EDDPEATyTTSGGKI | dephosphorylation down-regulates activity | 21538645 | SIGNOR-246027 |
| EPHA2 | EPHA2 | Tyr772 | EDDPEATyTTSGGKI | phosphorylation up-regulates | 18387945 | SIGNOR-178181 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ACP1 | dephosphorylation down-regulates ⊣ | EPHA2 PTyr772 | dephosphorylation up-regulates → | EPHA2 | 21538645 | SIGNOR-246027 |
| EPHA2 | phosphorylation up-regulates → | EPHA2 PTyr772 | phosphorylation up-regulates → | EPHA2 | 18387945 | SIGNOR-178181 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ACP1 | dephosphorylation → down-regulates activity | EPHA2 | SIGNOR-246027 |
| EPHA2 | phosphorylation → up-regulates | EPHA2 | SIGNOR-178181 |
