Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
EPHB2	SYNJ1	–		phosphorylation down-regulates	15821731	SIGNOR-135274
EPHB2	MYO1B	–		phosphorylation up-regulates activity	26195670	SIGNOR-279171
EPHB2	ARHGEF15	Tyr353	PLQDEPLyQTYRAAV	phosphorylation down-regulates quantity by destabilization	21029865	SIGNOR-262864
EPHB2	RRAS	Tyr66	DPTIEDSyTKICSVD	phosphorylation down-regulates activity	10570155	SIGNOR-251125
EPHB2	EPHB2	Tyr602	IYIDPFTyEDPNEAV	phosphorylation up-regulates activity	10572014	SIGNOR-251124
EPHB2	GRIN2B	Tyr1474	GSSNGHVyEKLSSIE	phosphorylation up-regulates quantity	33661095	SIGNOR-279710
EPHB2	NRCAM	Tyr1276	DGSFIGQySGKKEKE	phosphorylation up-regulates activity	24023801	SIGNOR-262863

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
EPHB2	phosphorylation up-regulates →	ARHGEF15 PTyr353	phosphorylation down-regulates ⊣	ARHGEF15	21029865	SIGNOR-262864
EPHB2	phosphorylation up-regulates →	RRAS PTyr66	phosphorylation down-regulates ⊣	RRAS	10570155	SIGNOR-251125
EPHB2	phosphorylation up-regulates →	EPHB2 PTyr602	phosphorylation up-regulates →	EPHB2	10572014	SIGNOR-251124
EPHB2	phosphorylation up-regulates →	GRIN2B PTyr1474	phosphorylation up-regulates →	GRIN2B	33661095	SIGNOR-279710
EPHB2	phosphorylation up-regulates →	NRCAM PTyr1276	phosphorylation up-regulates →	NRCAM	24023801	SIGNOR-262863

Regulator	Mechanism/Effect	Target	SIGNOR-ID
EPHB2	phosphorylation down-regulates	SYNJ1	SIGNOR-135274
EPHB2	phosphorylation → up-regulates activity	MYO1B	SIGNOR-279171
EPHB2	phosphorylation down-regulates quantity by destabilization	ARHGEF15	SIGNOR-262864
EPHB2	phosphorylation → down-regulates activity	RRAS	SIGNOR-251125
EPHB2	phosphorylation → up-regulates activity	EPHB2	SIGNOR-251124
EPHB2	phosphorylation → up-regulates quantity	GRIN2B	SIGNOR-279710
EPHB2	phosphorylation → up-regulates activity	NRCAM	SIGNOR-262863