Entity Details

Name KDM5A
ID P29375
Role substrate
Enzymatic Domains
JmjN 19-60
PROSITE-ProRule
ARID 84-174
PROSITE-ProRule
JmjC 437-603
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1KDM5AThr285QMRQRKGtLSVNFVDphosphorylation
up-regulates activity		27292631SIGNOR-274061
AKT1KDM5ASer225
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TRRVKTQsESGDVSRphosphorylation
up-regulates activity		27292631SIGNOR-274060
AKT1KDM5ASer1255CLTERAMsWQDRARQphosphorylation
up-regulates activity		27292631SIGNOR-274059
AKT1KDM5AThr1225SRRPRLEtILSLLVSphosphorylation
up-regulates activity		27292631SIGNOR-274063
AKT1KDM5ASer287RQRKGTLsVNFVDLYphosphorylation
up-regulates activity		27292631SIGNOR-274062
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
KDM5A
PThr285		phosphorylation
up-regulates
→		KDM5A27292631SIGNOR-274061
AKT1phosphorylation
up-regulates
→
KDM5A
PSer225		phosphorylation
up-regulates
→		KDM5A27292631SIGNOR-274060
AKT1phosphorylation
up-regulates
→
KDM5A
PSer1255		phosphorylation
up-regulates
→		KDM5A27292631SIGNOR-274059
AKT1phosphorylation
up-regulates
→
KDM5A
PThr1225		phosphorylation
up-regulates
→		KDM5A27292631SIGNOR-274063
AKT1phosphorylation
up-regulates
→
KDM5A
PSer287		phosphorylation
up-regulates
→		KDM5A27292631SIGNOR-274062
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
→
up-regulates activity 		KDM5ASIGNOR-274061
AKT1phosphorylation
→
up-regulates activity 		KDM5ASIGNOR-274060
AKT1phosphorylation
→
up-regulates activity 		KDM5ASIGNOR-274059
AKT1phosphorylation
→
up-regulates activity 		KDM5ASIGNOR-274063
AKT1phosphorylation
→
up-regulates activity 		KDM5ASIGNOR-274062