Entity Details

Name TKT
ID P29401
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTTKTThr382GCATRNRtVPFCSTFphosphorylation
up-regulates activity		24981175SIGNOR-265102
VRK2TKTThr287
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SKKKILAtPPQEDAPphosphorylation
up-regulates activity		37653031SIGNOR-277842
AKT1TKTThr382GCATRNRtVPFCSTFphosphorylation
up-regulates activity		24981175SIGNOR-265101
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
TKT
PThr382		phosphorylation
up-regulates
→		TKT24981175SIGNOR-265102
VRK2phosphorylation
up-regulates
→
TKT
PThr287		phosphorylation
up-regulates
→		TKT37653031SIGNOR-277842
AKT1phosphorylation
up-regulates
→
TKT
PThr382		phosphorylation
up-regulates
→		TKT24981175SIGNOR-265101
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
up-regulates activity 		TKTSIGNOR-265102
VRK2phosphorylation
→
up-regulates activity 		TKTSIGNOR-277842
AKT1phosphorylation
→
up-regulates activity 		TKTSIGNOR-265101