Entity Details

Name ABL1_Tyr81
ID P29474
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCNOS3Tyr81WEVGSITyDTLSAQAphosphorylation
up-regulates activity		32653904SIGNOR-277520
PTPRBNOS3Tyr81WEVGSITyDTLSAQAdephosphorylation
down-regulates activity		32653904SIGNOR-277041
ABL1NOS3Tyr81WEVGSITyDTLSAQAphosphorylation
up-regulates activity		32653904SIGNOR-277519
PTPRBNOS3Tyr81WEVGSITyDTLSAQAdephosphorylation
down-regulates activity		32653904SIGNOR-277521
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
NOS3
PTyr81		phosphorylation
up-regulates
→		NOS332653904SIGNOR-277520
PTPRBdephosphorylation
down-regulates
⊣
NOS3
PTyr81		dephosphorylation
up-regulates
→		NOS332653904SIGNOR-277041
ABL1phosphorylation
up-regulates
→
NOS3
PTyr81		phosphorylation
up-regulates
→		NOS332653904SIGNOR-277519
PTPRBdephosphorylation
down-regulates
⊣
NOS3
PTyr81		dephosphorylation
up-regulates
→		NOS332653904SIGNOR-277521
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		NOS3SIGNOR-277520
PTPRBdephosphorylation
→
down-regulates activity 		NOS3SIGNOR-277041
ABL1phosphorylation
→
up-regulates activity 		NOS3SIGNOR-277519
PTPRBdephosphorylation
→
down-regulates activity 		NOS3SIGNOR-277521