| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK5 | NOS3 | Ser114 | RKLQGRPsPGPPAPE | phosphorylation down-regulates | 20213743 | SIGNOR-164080 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK5 | phosphorylation up-regulates → | NOS3 PSer114 | phosphorylation down-regulates ⊣ | NOS3 | 20213743 | SIGNOR-164080 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK5 | phosphorylation down-regulates | NOS3 | SIGNOR-164080 |
