| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8422248 | SIGNOR-248926 |
| PKN1 | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation down-regulates activity | 8557118 | SIGNOR-249651 |
| PKN1 | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation unknown | 8557118 | SIGNOR-248937 |
| PRKCA | MARCKS | Ser81 | AAGSGAAsPSAAEKG | phosphorylation unknown | 8034575 | SIGNOR-248910 |
| PRKCA | MARCKS | Ser46 | VKVNGDAsPAAAESG | phosphorylation unknown | 8034575 | SIGNOR-248908 |
| PRKCB | MARCKS | Ser170 | SFKLSGFsFKKNKKE | phosphorylation unknown | 8422248 | SIGNOR-248929 |
| PKN1 | MARCKS | Ser170 | SFKLSGFsFKKNKKE | phosphorylation down-regulates activity | 8557118 | SIGNOR-249671 |
| PRKCD | MARCKS | Ser170 | SFKLSGFsFKKNKKE | phosphorylation unknown | 8422248 | SIGNOR-248930 |
| PRKCB | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation unknown | 8422248 | SIGNOR-248923 |
| PRKCA | MARCKS | Ser101 | AAPEAGAsPVEKEAP | phosphorylation unknown | 8034575 | SIGNOR-248909 |
| PRKCA | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation down-regulates activity | 1560845 | SIGNOR-249650 |
| PKN1 | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation down-regulates activity | 8557118 | SIGNOR-243199 |
| PRKCD | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation unknown | 8422248 | SIGNOR-248924 |
| PRKCA | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation down-regulates activity | 1560845 | SIGNOR-243192 |
| PRKCA | MARCKS | Ser170 | SFKLSGFsFKKNKKE | phosphorylation unknown | 8422248 | SIGNOR-248931 |
| PRKCD | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8422248 | SIGNOR-248927 |
| PRKCA | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8422248 | SIGNOR-248928 |
| PRKCA | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation unknown | 16116087 | SIGNOR-139906 |
| PRKCA | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 16116087 | SIGNOR-139910 |
| PKN1 | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8557118 | SIGNOR-248938 |
| PRKCA | MARCKS | Ser118 | GEAAEPGsPTAAEGE | phosphorylation unknown | 8034575 | SIGNOR-248907 |
| PRKCA | MARCKS | Ser159 | KKKKKRFsFKKSFKL | phosphorylation unknown | 8422248 | SIGNOR-248925 |
| PKN1 | MARCKS | Ser170 | SFKLSGFsFKKNKKE | phosphorylation unknown | 8557118 | SIGNOR-248939 |
| PRKCA | MARCKS | Ser170 | SFKLSGFsFKKNKKE | phosphorylation down-regulates activity | 1560845 | SIGNOR-249670 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248926 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-249651 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-248937 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer81 | phosphorylation down-regulates ⊣ | MARCKS | 8034575 | SIGNOR-248910 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer46 | phosphorylation down-regulates ⊣ | MARCKS | 8034575 | SIGNOR-248908 |
| PRKCB | phosphorylation up-regulates → | MARCKS PSer170 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248929 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer170 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-249671 |
| PRKCD | phosphorylation up-regulates → | MARCKS PSer170 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248930 |
| PRKCB | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248923 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer101 | phosphorylation down-regulates ⊣ | MARCKS | 8034575 | SIGNOR-248909 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 1560845 | SIGNOR-249650 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-243199 |
| PRKCD | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248924 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 1560845 | SIGNOR-243192 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer170 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248931 |
| PRKCD | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248927 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248928 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 16116087 | SIGNOR-139906 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 16116087 | SIGNOR-139910 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-248938 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer118 | phosphorylation down-regulates ⊣ | MARCKS | 8034575 | SIGNOR-248907 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer159 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248925 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer170 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-248939 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer170 | phosphorylation down-regulates ⊣ | MARCKS | 1560845 | SIGNOR-249670 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation → unknown | MARCKS | SIGNOR-248926 |
| PKN1 | phosphorylation → down-regulates activity | MARCKS | SIGNOR-249651 |
| PKN1 | phosphorylation → unknown | MARCKS | SIGNOR-248937 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248910 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248908 |
| PRKCB | phosphorylation → unknown | MARCKS | SIGNOR-248929 |
| PKN1 | phosphorylation → down-regulates activity | MARCKS | SIGNOR-249671 |
| PRKCD | phosphorylation → unknown | MARCKS | SIGNOR-248930 |
| PRKCB | phosphorylation → unknown | MARCKS | SIGNOR-248923 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248909 |
| PRKCA | phosphorylation → down-regulates activity | MARCKS | SIGNOR-249650 |
| PKN1 | phosphorylation → down-regulates activity | MARCKS | SIGNOR-243199 |
| PRKCD | phosphorylation → unknown | MARCKS | SIGNOR-248924 |
| PRKCA | phosphorylation → down-regulates activity | MARCKS | SIGNOR-243192 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248931 |
| PRKCD | phosphorylation → unknown | MARCKS | SIGNOR-248927 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248928 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-139906 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-139910 |
| PKN1 | phosphorylation → unknown | MARCKS | SIGNOR-248938 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248907 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248925 |
| PKN1 | phosphorylation → unknown | MARCKS | SIGNOR-248939 |
| PRKCA | phosphorylation → down-regulates activity | MARCKS | SIGNOR-249670 |
