| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKN1 | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation down-regulates activity | 8557118 | SIGNOR-249651 |
| PRKCD | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8422248 | SIGNOR-248927 |
| PRKCA | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation down-regulates activity | 1560845 | SIGNOR-249650 |
| PRKCA | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 16116087 | SIGNOR-139910 |
| PRKCA | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8422248 | SIGNOR-248928 |
| PKN1 | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8557118 | SIGNOR-248938 |
| PRKCB | MARCKS | Ser163 | KRFSFKKsFKLSGFS | phosphorylation unknown | 8422248 | SIGNOR-248926 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKN1 | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-249651 |
| PRKCD | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248927 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 1560845 | SIGNOR-249650 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 16116087 | SIGNOR-139910 |
| PRKCA | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248928 |
| PKN1 | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8557118 | SIGNOR-248938 |
| PRKCB | phosphorylation up-regulates → | MARCKS PSer163 | phosphorylation down-regulates ⊣ | MARCKS | 8422248 | SIGNOR-248926 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKN1 | phosphorylation → down-regulates activity | MARCKS | SIGNOR-249651 |
| PRKCD | phosphorylation → unknown | MARCKS | SIGNOR-248927 |
| PRKCA | phosphorylation → down-regulates activity | MARCKS | SIGNOR-249650 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-139910 |
| PRKCA | phosphorylation → unknown | MARCKS | SIGNOR-248928 |
| PKN1 | phosphorylation → unknown | MARCKS | SIGNOR-248938 |
| PRKCB | phosphorylation → unknown | MARCKS | SIGNOR-248926 |
