| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROBO | CCND2 | Thr280 | DELDQAStPTDVRDI | phosphorylation down-regulates | 17486076 | SIGNOR-154672 |
| GSK3B | CCND2 | Thr280 | DELDQAStPTDVRDI | phosphorylation down-regulates | 17486076 | SIGNOR-154668 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ROBO | phosphorylation up-regulates → | CCND2 PThr280 | phosphorylation down-regulates ⊣ | CCND2 | 17486076 | SIGNOR-154672 |
| GSK3B | phosphorylation up-regulates → | CCND2 PThr280 | phosphorylation down-regulates ⊣ | CCND2 | 17486076 | SIGNOR-154668 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ROBO | phosphorylation![]() down-regulates | CCND2 | SIGNOR-154672 |
| GSK3B | phosphorylation![]() down-regulates | CCND2 | SIGNOR-154668 |