Entity Details

Name CCND3
ID P30281
Role substrate
Enzymatic Domains
Cyclin N-terminal 27-152
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PP1CCND3Thr283 QGPSQTStPTDVTAIdephosphorylation
up-regulates
16331257SIGNOR-264662
GSK3BCCND3Thr283 QGPSQTStPTDVTAIphosphorylation
down-regulates
16331257SIGNOR-142880
ROBOCCND3Thr283 QGPSQTStPTDVTAIphosphorylation
down-regulates
15326477SIGNOR-128402
PPP1CACCND3Thr283 QGPSQTStPTDVTAIdephosphorylation
up-regulates
16331257SIGNOR-142884
MAPK11CCND3Thr283 QGPSQTStPTDVTAIphosphorylation
down-regulates quantity by destabilization
15326477SIGNOR-280023
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PP1dephosphorylation
down-regulates
⊣
CCND3
PThr283
dephosphorylation
down-regulates
⊣
CCND316331257SIGNOR-264662
GSK3Bphosphorylation
up-regulates
→
CCND3
PThr283
phosphorylation
down-regulates
⊣
CCND316331257SIGNOR-142880
ROBOphosphorylation
up-regulates
→
CCND3
PThr283
phosphorylation
down-regulates
⊣
CCND315326477SIGNOR-128402
PPP1CAdephosphorylation
down-regulates
⊣
CCND3
PThr283
dephosphorylation
down-regulates
⊣
CCND316331257SIGNOR-142884
MAPK11phosphorylation
up-regulates
→
CCND3
PThr283
phosphorylation
down-regulates
⊣
CCND315326477SIGNOR-280023
Regulator Mechanism/Effect Target SIGNOR-ID
PP1dephosphorylation
→
up-regulates
CCND3SIGNOR-264662
GSK3Bphosphorylation
img/direct_inhibition.png
down-regulates
CCND3SIGNOR-142880
ROBOphosphorylation
img/direct_inhibition.png
down-regulates
CCND3SIGNOR-128402
PPP1CAdephosphorylation
→
up-regulates
CCND3SIGNOR-142884
MAPK11phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
CCND3SIGNOR-280023