Entity Details

Name CDK2_Ser123
ID P30291
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary

Notice: Undefined variable: effectA in /home/prisca/signor/PhosphoSIGNOR/results/entity.php on line 477

Notice: Undefined variable: effectB in /home/prisca/signor/PhosphoSIGNOR/results/entity.php on line 478

Notice: Undefined variable: effectA in /home/prisca/signor/PhosphoSIGNOR/results/entity.php on line 487

Notice: Undefined variable: effectB in /home/prisca/signor/PhosphoSIGNOR/results/entity.php on line 493
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK2WEE1Ser123EEGFGSSsPVKSPAA
down-regulates quantity by destabilization		16085715SIGNOR-276039
CDC14AWEE1Ser123EEGFGSSsPVKSPAAdephosphorylation
up-regulates quantity by stabilization		23051732SIGNOR-276952
CDK1WEE1Ser123EEGFGSSsPVKSPAAphosphorylation
down-regulates		15070733SIGNOR-123824
PLK1WEE1Ser123EEGFGSSsPVKSPAAphosphorylation
down-regulates		16085715SIGNOR-139473
CDC14AWEE1Ser123EEGFGSSsPVKSPAAdephosphorylation
up-regulates quantity by stabilization		23051732SIGNOR-267469
CDK1WEE1Ser123EEGFGSSsPVKSPAAphosphorylation
down-regulates		16085715SIGNOR-139465
CDK2WEE1Ser123EEGFGSSsPVKSPAAphosphorylation
down-regulates		16085715SIGNOR-139469
CyclinB/CDK1WEE1Ser123EEGFGSSsPVKSPAAphosphorylation
down-regulates quantity by destabilization		23051732SIGNOR-267471
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK2

⊣
WEE1
PSer123

⊣		WEE116085715SIGNOR-276039
CDC14Adephosphorylation
down-regulates
⊣
WEE1
PSer123		dephosphorylation
down-regulates
⊣		WEE123051732SIGNOR-276952
CDK1phosphorylation
up-regulates
→
WEE1
PSer123		phosphorylation
down-regulates
⊣		WEE115070733SIGNOR-123824
PLK1phosphorylation
up-regulates
→
WEE1
PSer123		phosphorylation
down-regulates
⊣		WEE116085715SIGNOR-139473
CDC14Adephosphorylation
down-regulates
⊣
WEE1
PSer123		dephosphorylation
down-regulates
⊣		WEE123051732SIGNOR-267469
CDK1phosphorylation
up-regulates
→
WEE1
PSer123		phosphorylation
down-regulates
⊣		WEE116085715SIGNOR-139465
CDK2phosphorylation
up-regulates
→
WEE1
PSer123		phosphorylation
down-regulates
⊣		WEE116085715SIGNOR-139469
CyclinB/CDK1phosphorylation
up-regulates
→
WEE1
PSer123		phosphorylation
down-regulates
⊣		WEE123051732SIGNOR-267471
Regulator Mechanism/Effect Target SIGNOR-ID
CDK2
img/direct_inhibition.png
down-regulates quantity by destabilization 		WEE1SIGNOR-276039
CDC14Adephosphorylation
→
up-regulates quantity by stabilization 		WEE1SIGNOR-276952
CDK1phosphorylation
img/direct_inhibition.png
down-regulates 		WEE1SIGNOR-123824
PLK1phosphorylation
img/direct_inhibition.png
down-regulates 		WEE1SIGNOR-139473
CDC14Adephosphorylation
→
up-regulates quantity by stabilization 		WEE1SIGNOR-267469
CDK1phosphorylation
img/direct_inhibition.png
down-regulates 		WEE1SIGNOR-139465
CDK2phosphorylation
img/direct_inhibition.png
down-regulates 		WEE1SIGNOR-139469
CyclinB/CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		WEE1SIGNOR-267471