| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | CDC25A | Thr507 | KFRTKSRtWAGEKSK | phosphorylation down-regulates | 20068082 | SIGNOR-163154 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | phosphorylation up-regulates → | CDC25A PThr507 | phosphorylation down-regulates ⊣ | CDC25A | 20068082 | SIGNOR-163154 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHEK1 | phosphorylation down-regulates | CDC25A | SIGNOR-163154 |
