Entity Details

Name CHEK2_Ser279
ID P30304
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHEK1CDC25ASer279VLKRPERsQEESPPGphosphorylation
down-regulates		20068082SIGNOR-163142
CHEK2CDC25ASer279VLKRPERsQEESPPGphosphorylation
down-regulates quantity by destabilization		12676583SIGNOR-99729
CHEK2CDC25ASer279VLKRPERsQEESPPGphosphorylation
down-regulates quantity		12676583SIGNOR-260834
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CHEK1phosphorylation
up-regulates
→
CDC25A
PSer279		phosphorylation
down-regulates
⊣		CDC25A20068082SIGNOR-163142
CHEK2phosphorylation
up-regulates
→
CDC25A
PSer279		phosphorylation
down-regulates
⊣		CDC25A12676583SIGNOR-99729
CHEK2phosphorylation
up-regulates
→
CDC25A
PSer279		phosphorylation
down-regulates
⊣		CDC25A12676583SIGNOR-260834
Regulator Mechanism/Effect Target SIGNOR-ID
CHEK1phosphorylation
img/direct_inhibition.png
down-regulates 		CDC25ASIGNOR-163142
CHEK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDC25ASIGNOR-99729
CHEK2phosphorylation
→
down-regulates quantity 		CDC25ASIGNOR-260834