Entity Details

Name CyclinD3/CDK6_Ser40
ID P30304
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinD3/CDK6CDC25ASer40ASAAGGLsPVTNLTVphosphorylation
down-regulates quantity by destabilization		28192398SIGNOR-277343
CyclinD/CDK4CDC25ASer40ASAAGGLsPVTNLTVphosphorylation
down-regulates quantity by destabilization		28192398SIGNOR-277340
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinD3/CDK6phosphorylation
up-regulates
→
CDC25A
PSer40		phosphorylation
down-regulates
⊣		CDC25A28192398SIGNOR-277343
CyclinD/CDK4phosphorylation
up-regulates
→
CDC25A
PSer40		phosphorylation
down-regulates
⊣		CDC25A28192398SIGNOR-277340
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinD3/CDK6phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDC25ASIGNOR-277343
CyclinD/CDK4phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDC25ASIGNOR-277340