Entity Details

Name DYRK2_Ser18
ID P30304
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1CDC25ASer18RRLLFACsPPPASQPphosphorylation
up-regulates		12411508SIGNOR-95260
DYRK2CDC25ASer18RRLLFACsPPPASQPphosphorylation
down-regulates quantity by destabilization		34363019SIGNOR-276736
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
CDC25A
PSer18		phosphorylation
up-regulates
→		CDC25A12411508SIGNOR-95260
DYRK2phosphorylation
up-regulates
→
CDC25A
PSer18		phosphorylation
down-regulates
⊣		CDC25A34363019SIGNOR-276736
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates 		CDC25ASIGNOR-95260
DYRK2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDC25ASIGNOR-276736