| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6K | CDC25A | Ser295 | TKRRKSMsGASPKES | phosphorylation down-regulates | 23708659 | SIGNOR-252776 |
| RPS6KA1 | CDC25A | Ser295 | TKRRKSMsGASPKES | phosphorylation down-regulates | 23708659 | SIGNOR-202117 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6K | phosphorylation up-regulates → | CDC25A PSer295 | phosphorylation down-regulates ⊣ | CDC25A | 23708659 | SIGNOR-252776 |
| RPS6KA1 | phosphorylation up-regulates → | CDC25A PSer295 | phosphorylation down-regulates ⊣ | CDC25A | 23708659 | SIGNOR-202117 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6K | phosphorylation![]() down-regulates | CDC25A | SIGNOR-252776 |
| RPS6KA1 | phosphorylation![]() down-regulates | CDC25A | SIGNOR-202117 |