| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | CDC25B | Ser230 | AFAQRPSsAPDLMCL | phosphorylation down-regulates activity | 17003105 | SIGNOR-149898 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHEK1 | phosphorylation up-regulates → | CDC25B PSer230 | phosphorylation down-regulates ⊣ | CDC25B | 17003105 | SIGNOR-149898 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHEK1 | phosphorylation → down-regulates activity | CDC25B | SIGNOR-149898 |
