| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| p38 | CDC25B | Ser103 | ESSLSSEsSESSDAG | phosphorylation down-regulates quantity by destabilization | 21807946 | SIGNOR-276349 |
| MAPK8 | CDC25B | Ser103 | ESSLSSEsSESSDAG | phosphorylation down-regulates quantity by destabilization | 21807946 | SIGNOR-276351 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| p38 | phosphorylation up-regulates → | CDC25B PSer103 | phosphorylation down-regulates ⊣ | CDC25B | 21807946 | SIGNOR-276349 |
| MAPK8 | phosphorylation up-regulates → | CDC25B PSer103 | phosphorylation down-regulates ⊣ | CDC25B | 21807946 | SIGNOR-276351 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| p38 | phosphorylation![]() down-regulates quantity by destabilization | CDC25B | SIGNOR-276349 |
| MAPK8 | phosphorylation![]() down-regulates quantity by destabilization | CDC25B | SIGNOR-276351 |